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Engineering Escherichia coli for the S-selective production of 2-hydroxyisovalerate

Peiling Wu Shizhen Wang Jifeng Yuan Haofeng Chen Guojun Yang Haoyu Qin Qian Zhang Yuxin Chen Dongjiang Lin Yang Zhang Shuyong Lin

生物设计研究（英文）2025，Vol.7Issue(4)：47-55,9.

生物设计研究（英文）2025，Vol.7Issue(4)：47-55,9.DOI:10.1016/j.bidere.2025.100059

Engineering Escherichia coli for the S-selective production of 2-hydroxyisovalerate

Peiling Wu ¹Shizhen Wang ²Jifeng Yuan ¹Haofeng Chen ¹Guojun Yang ¹Haoyu Qin ¹Qian Zhang ²Yuxin Chen ²Dongjiang Lin ¹Yang Zhang ¹Shuyong Lin¹

作者信息

1. State Key Laboratory of Cellular Stress Biology,School of Life Sciences,Faculty of Medicine and Life Sciences,Xiamen University,Fujian,361102,China
2. College of Chemistry and Chemical Engineering,Xiamen University,Fujian,361005,China
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摘要

关键词

2-Hydroxyisovalerate/4-Hydroxymandelate synthase/Protein engineering/de novo production/Synthetic biology

Key words

2-Hydroxyisovalerate/4-Hydroxymandelate synthase/Protein engineering/de novo production/Synthetic biology

引用本文复制引用

Peiling Wu,Shizhen Wang,Jifeng Yuan,Haofeng Chen,Guojun Yang,Haoyu Qin,Qian Zhang,Yuxin Chen,Dongjiang Lin,Yang Zhang,Shuyong Lin..Engineering Escherichia coli for the S-selective production of 2-hydroxyisovalerate[J].生物设计研究（英文）,2025,7(4):47-55,9.

基金项目

This work was supported by the National Key R&D Program of China(grant no.:2024YFC3407000),the National Natural Science Foundation of China(grant no.:32270087),the Fundamental Research Funds for the Central Universities(grant no.:20720240120),and ZhenSheng Biotech. （grant no.:2024YFC3407000）

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