烟草科技2026，Vol.59Issue(3)：10-20,11.DOI:10.16135/j.issn1002-0861.2025.0539
基于大体积热进样-柱内蒸发浓缩技术的鼻后呼出气溶胶成分分析
Component analysis of postnasal exhaled aerosols based on large volume thermal injection and in-column evaporative concentration technique
摘要
Abstract
To characterize the composition of postnasal exhaled aerosols(PEAs)from smokers,an analytical method based on large-volume thermal injection followed by in-column evaporative concentration was developed.By using this novel PEA collection device under optimized parameters,the exhaled aerosol components by smokers using either Virginia type and US blended type cigarettes were analyzed and compared.In addition,a smoking machine was employed to replicate actual smoker's puffing profiles to quantify the releases of inhaled aerosol components which were then compared with those of the PEA components.The results showed that:1)A total of 158 chemical components were detected in the PEAs,with relative standard deviations(RSDs)all below 15%,among which 100 were with RSDs below 10%;2)For both Virginia type and blended type cigarettes,the releases of aerosol components from PEAs were significantly lower than those of retrohaling PEAs.The average retention rates across different chemical categories were not significantely different during inhalation,while significant differences were observed among cigarette categories during retrohaling.3)Inter-individual variations in aerosol retention rates were relatively small during the smoking of both Virgina type and blended type cigarettes,while differences in retention rates due to smoking behaviors were more pronounced.关键词
卷烟/吸烟者/气溶胶/大循环/小循环/鼻后呼出/大体积进样/柱内蒸发浓缩Key words
Cigarette/Smoker/Aerosol/Inhalation/Retrohaling/Postnasal exhalation/Large volume injection/In-column evaporative concentration分类
轻工纺织引用本文复制引用
李俊杰,戚大伟,程乾,吴达,张玮,杜淮清,王嘉乐,周妍,顾文博..基于大体积热进样-柱内蒸发浓缩技术的鼻后呼出气溶胶成分分析[J].烟草科技,2026,59(3):10-20,11.基金项目
中国烟草总公司科技项目"基于烟气化学成分的感官表征技术研究"[110202401028(SZ-02)]. （SZ-02）
