中国实验动物学报2026，Vol.34Issue(2)：257-263,7.DOI:10.3969/j.issn.1005-4847.2026.02.011
血压变异性升高大鼠模型构建研究进展
Research progress on construction of rat models with elevated blood pressure variability
摘要
Abstract
The increased of blood pressure variability(BPV)plays important role in the occurrence and development of target organs such as heart,brain,kidney and blood vessel damage in hypertensive population,controlling BPV is an effective method to reduce the incidence of cardiovascular events and mortality in patients with hypertensive.Through literature mining and collation,this article reviews the construction methods and model characteristics of rat models with increased BPV,in order to provide references for experimental research on BPV elevation.关键词
高血压/血压变异性/大鼠模型/研究进展Key words
hypertension/blood pressure variability/rat model/research progress分类
生物科学引用本文复制引用
杜丽东,杜玉姣,石磊,翟婉莹,杨志军,赵英,郭娇宏,吴国泰..血压变异性升高大鼠模型构建研究进展[J].中国实验动物学报,2026,34(2):257-263,7.基金项目
甘肃省高等学校创新基金项目(2021A-080),甘肃省教育科技创新项目(2022A-068),甘肃省中药药理与毒理重点实验室开放基金项目(ZDSYS-KJ-2024-003).Funded by Gansu Province Higher Education Innovation Project(2021A-080),Gansu Province Education Technology Innovation Project(2022A-068),Open Fund Project of Key Laboratory of Traditional Chinese Medicine Pharmacology and Toxicology in Gansu Province(ZDSYS-KJ-2024-003). （2021A-080）
