中华中医药杂志2026，Vol.41Issue(1)：49-53,5.
络玄府病理探微
Exploration on the pathological mechanisms of Luo Xuanfu
摘要
Abstract
The Luo Xuanfu,as the microscopic structural unit of the collateral meridian system,forms a three-dimensional network with the Xuanfu(pores)and collaterals,whose core function is to regulate qi-blood transformation and essence distribution through the'gathering-dispersing and opening-closing'dual axis mechanism.Building on previous physiological studies,this research further elucidates its pathological characteristics:Luo Xuanfu stagnation serves as the initiating factor for diseases,while'defects in gathering-dispersing'and'dy-sregulation of opening-closing'constitute critical progression stages.The former manifests as qi-blood mutual transformation disorders,while the latter leads to essence distribution imbalances.These two pathological processes reciprocally reinforce each other,forming a vicious cycle that drives disease pathogenesis.In response,this study proposes a novel therapeutic framework centered on'opening and activating the Luo Xuanfu',with two core strategies:'regulating qi and harmonizing form'and'promoting dispersion and unblocking'(pathway clearance).Complementary therapies:including tonifying deficiency and removing stagnation,eliminating dampness and promoting water transformation,heat-clearing and fire-purging,eliminating phlegm and clearing up turbid,and activating blood and removing toxin,are tailored to specific pathogenic products.Additionally,insect ant based therapies are employed to improve microcirculation.Through the synergistic application of these three therapeutic approaches that act in a targeted manner on the Luo-Xuanfu,we break through the cognitive limitation that the traditional Xuanfu merely governs the circulation of qi and body fluids,resolve the inherent contradictions of simple unblocking therapy,such as'deficiency of nourishment after unblocking'and'subsequent tissue damage after unblocking',and establish a microscopic regulatory mechanism for form-qi transformation as well as a dual-axis treatment system based on'gathering-dispersing and opening-closing',thereby providing innovative insights for the clinical management of complex refractory diseases.关键词
络玄府/聚散/开阖/形气互化Key words
Luo Xuanfu/Gathering-dispersion/Opening-closing/Form-qi Transformation引用本文复制引用
曹兴旺,董丽,姚明月,毕涛,蒲玥衡,张思敏,李珊,陈皓灵,王明杰,李波..络玄府病理探微[J].中华中医药杂志,2026,41(1):49-53,5.基金项目
西南医科大学中西医结合专项科研项目(No.2025ZXYZX04),泸州市人民政府西南医科大学科技战略合作项目(No.2025LZXNYDJC08),西南医科大学中西医结合专项重点项目(No.2024ZXYZX01) （No.2025ZXYZX04）
