中国比较医学杂志2026，Vol.36Issue(4)：85-92,8.DOI:10.3969/j.issn.1671-7856.2026.04.008
猴B病毒暴露人群职业健康安全管理及应急处理策略
Strategies for occupational health and safety and emergency management in humans exposed to monkey B virus
摘要
Abstract
Macaques are widely used as experimental animals in biomedical research.Monkey B virus(BV)is a zoonotic pathogen that naturally infects macaques,with an infection rate as high as 70％to 100％.Although BV infection in macaques is usually asymptomatic or has only mild symptoms,once transmitted to humans,it can cause severe encephalomyelitis and neurological sequelae,with a fatality rate of over 40％.BV can also remain latent in the human body for a long time and then be reactivated under specific circumstances,leading to serious neurological diseases.Most people infected with BV are animal caregivers,veterinarians,and laboratory researchers.The severity of human BV infection makes it the main zoonotic disease of concern among those in contact with macaques.There is currently no vaccine to prevent human infection with BV and no specific antiviral drugs.Implementing preventive measures through occupational health and safety management,conducting standardized emergency responses to exposure incidents,and promptly blocking or reducing the invasion of BV are thus key strategies for lowering the risk of human BV infection and mortality.This article reviews the characteristics of human BV infection,the preventive measures for occupational health and safety management related to BV,emergency treatment measures after exposure,exposure risk assessment,post-exposure prophylaxis,and the key points of post-exposure follow-up,with the aim of providing useful references for laboratory animal institutions and medical institutions in the practice of BV prevention and control.关键词
猴B病毒/职业暴露/职业健康安全/应急处理/策略Key words
monkey B virus/occupational exposure/occupational health and safety/emergency management/strategy分类
医药卫生引用本文复制引用
林丹荣,黄曼琪,杨锦淳,陈琳,李会萍,邓少嫦..猴B病毒暴露人群职业健康安全管理及应急处理策略[J].中国比较医学杂志,2026,36(4):85-92,8.基金项目
广东省科技计划项目(2021B1212060002) （2021B1212060002）
广州市科技计划项目(2023B03J1257). （2023B03J1257）
