中国比较医学杂志2026，Vol.36Issue(4)：93-99,7.DOI:10.3969/j.issn.1671-7856.2026.04.009
Gas7在神经系统中的研究进展
Research progress on growth arrest-specific protein 7 in the nervous system
摘要
Abstract
Growth arrest-specific protein 7(Gas7)is rich in α-helix structures and is highly expressed in the central nervous system,particularly in the cortex,hippocampus,and cerebellum.The abnormal expression of Gas7 is closely related to the occurrence of various nervous system diseases and drug addiction;however,the molecular regulation and underlying mechanisms of Gas 7 remain to be fully elucidated.This review comprehensively examines the diverse functions of Gas7 in the nervous system,including its critical regulatory roles in nervous system development,neuronal differentiation and maturation,microtubule dynamics,cell cycle regulation,neuronal migration,axon guidance,neuronal mitophagy and repair,and synaptic plasticity.Further investigations may offer novel insights into the pathogenesis of neurological diseases and provide a theoretical foundation for the development of innovative therapeutic strategies.关键词
毒品成瘾/Gas7/神经系统/突触可塑性Key words
drug addiction/Gas7/nervous system/synaptic plasticity分类
医药卫生引用本文复制引用
许睿珂,普珊,李韵兰,洪仕君,李利华,杨根梦..Gas7在神经系统中的研究进展[J].中国比较医学杂志,2026,36(4):93-99,7.基金项目
国家自然科学基金(82202081) （82202081）
云南省科技厅基础研究项目(202301AT070269,202301AU070216) （202301AT070269,202301AU070216）
云南省科技厅-昆医联合专项(202301AY070001-234). （202301AY070001-234）
