中国中西医结合影像学杂志2026，Vol.24Issue(2)：207-211,5.DOI:10.3969/j.issn.1672-0512.2026.02.016
Ki-67高表达胃肠道间质瘤CT增强扫描特征影响因素分析
Influencing factors associated with high Ki-67 expression in gastrointestinal stromal tumors based on CT enhancement features
摘要
Abstract
Objective:To investigate CT features associated with high Ki-67 expression in gastrointestinal stromal tumor(GIST)and to identify potential imaging influencing factors.Methods:The clinical and CT data of 191 GIST patients were collected.All patients were stratified into a high expression group(71 cases,Ki-67＞5%)and a low expression group(120 cases,Ki-67≤5%).Comparative analysis of CT qualitative and quantitative characteristics between the two groups was executed.Spearman correlation analysis was used to analyze the CT features related to the high Ki-67 expression.Binary logistic regression analysis was employed to ascertain the influencing factors associated with high Ki-67 expression in GIST.Results:Statistically significant differences were identified in tumor maximum and minimum diameters,risk grade,growth pattern,cystic degeneration,enhancement degree and rate in the portal venous phase between the two groups(all P＜0.05).These CT features exhibited a weak correlation with high Ki-67 expression(r=0.147-0.371).Logistic regression analysis revealed that intermediate/high risk grade,maximum diameter(＞5.85 cm),minimum diameter(＞2.95 cm),intraluminal growth pattern,cystic degeneration,enhancement degree(＞58.25 HU)and enhancement rate(＞1.73)in the portal venous phase were the independent influencing factors for high Ki-67 expression in GIST.Conclusions:Intermediate/high risk grade,maximum diameter(＞5.85 cm),minimum diameter(＞2.95 cm),intraluminal growth pattern,cystic degeneration,enhancement degree(＞58.25 HU)and enhancement rate(＞1.73)in the portal venous phase are the independent influencing factors for high Ki-67 expression in GIST.关键词
胃肠道间质瘤/Ki-67/体层摄影术,X线计算机/影响因素Key words
Gastrointestinal stromal tumor/Ki-67/Tomography,X-ray computed/Influencing factors分类
医药卫生引用本文复制引用
张雄,黄送,吴海辉,李思恩,林裕霖,朱志强,李玉林,杨志企..Ki-67高表达胃肠道间质瘤CT增强扫描特征影响因素分析[J].中国中西医结合影像学杂志,2026,24(2):207-211,5.基金项目
广东省医学科研基金项目(B2023445) （B2023445）
梅州市社会发展科技计划项目(2023B16). （2023B16）
