中国中医药科技2026，Vol.33Issue(1)：20-25,6.
黄芪汤固体饮料制备工艺研究
Study on the Preparation Process of Huangqi Decoction(黄芪汤)Solid Drink
摘要
Abstract
Objective:Develop a solid beverage to alleviate constipation based on the classic formula Huangqi Decoction,and optimize the preparation process.Methods:A single-factor combined response surface methodology was employed to investigate the interaction effects of three factors including solid-to-liquid ratio,number of decoctions,and decoction time,and total flavonoids,total saponins,and total polysaccharides were as response variables.This approach determined the optimal extraction process,with the content of total flavonoids,total saponins and total polysaccharides in the extract were measured by ultraviolet spectrophotometry.Using powder collection efficiency as the metric,a single-factor orthogonal design was employed to evaluate spray-drying processes for extraction solutions.Single-factor experiments screened excipients,with comprehensive scoring based on flowability,moisture absorption rate,solubility and sensory evaluation to determine the optimal formulation.Results:The optimal extraction process for Astragalus membranaceus decoction involves a solid-to-liquid ratio of 1∶15(g∶mL),with three decoction cycles of 80 minutes each.Spray drying parameters:inlet air temperature 180℃,fan frequency 65 Hz,feed flow rate 11 rpm.The optimal formulation for solid beverages:lactose as excipient with a drug-to-excipient ratio of 1∶0.7(g∶g)achieved the highest overall score.Conclusion:The preparation process of Astragalus Solid Beverage is stable,with excellent solubility and flowability,making it convenient for carrying and storage.关键词
黄芪汤/固体饮料/制备工艺/响应面法/喷雾干燥Key words
Huangqi Decoction/solid beverages/preparation process/response surface methodology/spray drying引用本文复制引用
佘春洁,赵娢,董坤,陈丽艳,王伟明..黄芪汤固体饮料制备工艺研究[J].中国中医药科技,2026,33(1):20-25,6.基金项目
黑龙江省中医药科研项目(ZHY2025-026) （ZHY2025-026）
现代农业产业技术体系建设专项(CARS-21) （CARS-21）
