中外医学研究2026，Vol.24Issue(6)：49-53,5.DOI:10.14033/j.cnki.cfmr.2026.06.014
多模态影像融合:CT灌注成像与MRI弥散加权成像在缺血性脑卒中评估中的协同作用与临床价值研究
Multimodal Image Fusion:A Study on the Synergistic Effects and Clinical Value of CT Perfusion Imaging and MRI Diffusion-Weighted Imaging in the Assessment of Ischemic Stroke
张国燕 1裴维邦 2李刚2
作者信息
- 1. 白银市中西医结合医院 甘肃 白银 730900
- 2. 白银市第一人民医院
- 折叠
摘要
Abstract
Objective:To investigate the clinical value of combining computed tomography perfusion(CTP)and diffusion-weighted imaging(DWI)in the evaluation of ischemic stroke.Method:A total of 120 patients with ischemic stroke admitted to Baiyin Hospital of Integrated Traditional Chinese and Western Medicine from December 2021 to December 2024 were enrolled.All patients underwent both CTP and MRI DWI examinations.The diagnostic efficacy of the two modalities for ischemic stroke,the assessment of the ischemic penumbra,and the correlation with clinical outcomes were analyzed.Result:The diagnostic efficacy of combining CTP with MRI DWI for ischemic stroke was significantly superior to either examination alone,demonstrating higher sensitivity and specificity.The AUC of the combined diagnosis reached 0.850,with statistically significant differences(P<0.05).Furthermore,the combined application allowed more accurate assessment of the ischemic penumbra,whose volume showed a significant positive correlation with the 90-day modified Rankin Scale score(r=0.678,P<0.001).Conclusion:The combination of CTP and MRI DWI provides a comprehensive evaluation of ischemic stroke from both hemodynamic and molecular diffusion perspectives,offering critical insights for clinical management and prognostic assessment.关键词
CT灌注/MRI弥散加权成像/缺血性脑卒中/缺血半暗带Key words
Computed tomography perfusion/MRI diffusion-weighted imaging/Ischemic stroke/Ischemic penumbra引用本文复制引用
张国燕,裴维邦,李刚..多模态影像融合:CT灌注成像与MRI弥散加权成像在缺血性脑卒中评估中的协同作用与临床价值研究[J].中外医学研究,2026,24(6):49-53,5.
