中医杂志2026，Vol.67Issue(4)：397-403,7.DOI:10.13288/j.11-2166/r.2026.04.010
功能性消化不良中西医诊疗及机制研究概况
Overview of Diagnosis,Treatment and Mechanism Research of Functional Dyspepsia by Integrated Traditional Chinese and Western Medicine
摘要
Abstract
Functional dyspepsia(FD)is a prioritized disease category where traditional Chinese medicine(TCM)demonstrates distinct therapeutic advantages.The current western medicine treatment for FD is mainly based on pro-ton pump inhibitors and prokinetic agents,with digestive enzymes,probiotics and antidepressants serving as adju-vant medication,yet such therapies still have certain limitations.TCM treatment for FD includes oral administration of Chinese herbal formulas and Chinese patent medicines,as well as external TCM therapies such as acupuncture and moxibustion,acupoint application,hot medicinal compress therapy,rubbing with ointment,medicinal iontophoresis,auricular acupoint therapy and tui na(Chinese medical massage).The combined treatment of FD with integrated TCM and western medicine can significantly improve clinical effectiveness and reduce adverse reactions.The common mechanisms underlying the therapeutic effects of both TCM and western medicine revolve around the core pathological processes of FD,mainly focusing on restoring gastrointestinal motility,regulating the levels of brain-gut peptides,modulating intestinal microecology,and ameliorating inflammatory status.The differential mechanisms lie in the pre-cise targeting feature of western medicine versus the holistic-regulating and multi-target characteristics of TCM,and the two approaches exert a synergistic effect to enhance efficacy.This paper proposes to leverage the advantages of TCM in holistic regulation and the strengths of western medicine in targeted treatment,so as to provide personalized and comprehensive treatment regimens for FD patients.关键词
功能性消化不良/中医药疗法/中西医结合疗法/文献综述Key words
functional dyspepsia/traditional Chinese medicine therapy/integrated traditional Chinese and western medicine therapy/literature review引用本文复制引用
张声生,刘凡,李双翼,唐旭东,时昭红,卢小芳,赵鲁卿,李丹艳,张书,赵璐,卓于迪,汪念..功能性消化不良中西医诊疗及机制研究概况[J].中医杂志,2026,67(4):397-403,7.基金项目
国家中医药管理局中医传承与创新"百千万"人才工程(岐黄学者)国家中医药领军人才支撑计划项目(国中医药人教函[2021]203号) （岐黄学者）
中国科学技术协会2024年中医脾胃病学学科发展研究(2024XKFZYJ) （2024XKFZYJ）
