中医杂志2026，Vol.67Issue(4)：432-438,7.DOI:10.13288/j.11-2166/r.2026.04.015
呼吸吐纳操在慢性阻塞性肺疾病急性加重期患者早期肺康复中的效果评价
Effectiveness Evaluation of Exhalation-Inhalation Exercise on Early Pulmonary Rehabilitation for Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
摘要
Abstract
Objective To evaluate the effectiveness of exhalation-inhalation exercise on early pulmonary rehabi-litation for patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods A total of 120 participants with AECOPD were randomly divided into a treatment group and a control group,with 60 partici-pants in each group.The control group treated with conventional western medicine,while the treatment group received exhalation-inhalation exercise training on the basis of conventional western medicine treatment,with 30 minutes per session and 5 sessions per week.The course of treatment for both groups was 12 weeks.The primary outcome was the 6-minute walking distance(6MWD).The secondary outcomes included pulmonary function indexes including forced expiratory volume in one second/forced vital capacity(FEV1/FVC),percentage of predicted forced expiratory volume in one second(FEV1％)and percentage of predicted forced vital capacity(FVC％),St.George's Respiratory Questionnaire(SGRQ)score,modified Medical Research Council(mMRC)dyspnea scale score,COPD assessment test(CAT)score,hospital anxiety and depression scale-anxiety subscale[HADS(A)]score,and hospital anxiety and depression scale-depression subscale[HADS(D)]score.Meanwhile,safety of all participants was recorded and assessed.Results During the treatment,12 participants dropped out from both the treatment group and the control group,with 48 participants in each group finally included in the analysis.The 6MWD of both groups after treatment was higher than that before treatment,and the 6MWD of the treatment group was higher than that of the control group(P＜0.05 or P＜0.01).After treatment,the SGRQ score,mMRC score and CAT score of the treatment group were lower than those before treatment,while FEV1％,FVC％and FEV1/FVC were higher than those before treatment(P＜0.05).Moreover,after treatment,the FEV1/FVC of the treatment group was higher than that of the control group,while the SGRQ score,mMRC score and CAT score were lower than those of the control group(P＜0.05 or P＜0.01).There was no statistically significant difference in pulmonary function indexes,SGRQ score,mMRC score and CAT score after treatment in the control group(P＞0.05).No statistically significant difference was observed in HADS(A)score and HADS(D)score after treatment within and between groups(P＞0.05).The incidence of adverse reactions in the treatment group was 6.25％(3/48),and 0 in the control group,with no statistically signifi-cant difference between groups(P＞0.05).Conclusion Exhalation-inhalation exercise for patients with AECOPD in early pulmonary rehabilitation can improve patients' exercise tole-rance,quality of life,clinical symptoms and pulmo-nary function,with good safety.关键词
慢性阻塞性肺疾病/急性加重期/肺康复/6分钟步行距离/肺功能/生活质量/呼吸吐纳操Key words
chronic obstructive pulmonary disease/acute exacerbation stage/pulmonary rehabilitation/6-minute walk distance/pulmonary function/quality of life/exhalation-inhalation exercise引用本文复制引用
王姣姣,韩林,周鹏程..呼吸吐纳操在慢性阻塞性肺疾病急性加重期患者早期肺康复中的效果评价[J].中医杂志,2026,67(4):432-438,7.基金项目
四川省干部保健科研课题(川干研2019-512) （川干研2019-512）
成都中医药大学"杏林学者"学科人才研究提升计划(XCZX2024002) （XCZX2024002）
