北京中医药2026，Vol.45Issue(1)：1-5,5.DOI:10.16025/j.1674-1307.2026.01.001
黄精降压汤联合氨氯地平治疗高血压病患者合并焦虑状态的效果观察
Clinical efficacy of Huangjing Jiangya Decoction combined with amlodipine in improving hypertensive patients with anxiety
摘要
Abstract
Objective To observe the clinical efficacy of Huangjing Jiangya Decoction combined with amlodipine in treating patients with hypertension complicated by anxiety.Methods A total of 71 patients with primary hypertension of qi-deficiency type and comorbid anxiety,treated at the Traditional Chinese Medicine,Cardiology,and Neurology Outpatient Departments of Beijing Sixth Hospital from May 2022 to November 2023,were randomly divided into an observation group and a control group.The control group received conventional Western medicine treatment with amlodipine besylate tablets 5 mg once daily.The observation group received additional oral administration of self-formulated Huangjing Jiangya Decoction on top of the control regimen.Both groups were treated continuously for 8 weeks.Clinical efficacy,clinic blood pressure,home blood pressure,24-hour ambulatory blood pressure,GAD-7 score,and TCM syndrome scores before and after treatment were compared between the two groups.Results After treatment,the total clinical efficacy and total TCM syndrome efficacy in the observation group were higher than those in the control group(both P<0.01).Clinic and home blood pressure in the observation group were significantly reduced compared to baseline(both P<0.05)and were lower than those in the control group(both P<0.01).The 24-hour systolic and diastolic blood pressure in the observation group decreased significantly compared to baseline(both P<0.05)and were lower than those in the control group(both P<0.01).The GAD-7 score and TCM syndrome scores in the observation group were significantly lower than before treatment(both P<0.05)and lower than in the control group(both P<0.01).No adverse reactions such as nausea or vomiting were observed during treatment,and liver and kidney function indicators remained normal in both groups.Conclusion Huangjing Jiangya Decoction combined with amlodipine can significantly reduce blood pressure,improve anxiety symptoms and clinical manifestations in patients with qi-deficiency hypertension and anxiety,with overall efficacy superior to amlodipine alone,and demonstrates high safety.关键词
高血压病合并焦虑状态/气虚证/黄精降压汤Key words
hypertension with anxiety/Qi-deficiency syndrome/Huangjing Jiangya Decoction引用本文复制引用
史雯,马海娟,何晋涛,董蕾,刘瑶,赵会灵,邢远..黄精降压汤联合氨氯地平治疗高血压病患者合并焦虑状态的效果观察[J].北京中医药,2026,45(1):1-5,5.基金项目
首都卫生发展科研专项项目(首发2022-2-7013) （首发2022-2-7013）
北京市东城区优秀人才培养资助项目(2022-dchrcpyzz-60) （2022-dchrcpyzz-60）
