北京中医药2026，Vol.45Issue(1)：16-21,6.DOI:10.16025/j.1674-1307.2026.01.004
鼻用皮质类固醇联合中药鼻腔冲洗治疗肺脾气虚型药物性鼻炎的疗效观察
Efficacy evaluation study on the treatment of rhinitis medicamentosa with nasal corticosteroids combined with traditional Chinese medicine nasal irrigation
摘要
Abstract
Objective To evaluate and compare the efficacy of nasal irrigation with Jiawei Yupingfeng and saline combined with nasal corticosteroids in the treatment of rhinitis medicamentosa.Methods A prospective controlled study was conducted at Wangjing Hospital of China Academy of Traditional Chinese Medicine from September 2023 to December 2024.The study included 84 patients diagnosed with Rhinitis medicamentosa and treated during this period.Patients were randomly divided into two groups:a saline rinse group and a traditional Chinese medicine rinse group.The randomization method used was a numerical table method.The saline rinse group was treated with saline nasal irrigation combined with nasal corticosteroids,while the traditional Chinese medicine rinse group was treated with Jiawei Yupingfeng nasal irrigation combined with nasal corticosteroids.The patients were followed up for a period of one month.The patients in the Chinese medicine rinsing group underwent a 2-week course of nasal irrigation with Jiawei yupingfeng in conjunction with nasal corticosteroids,followed by a 3-month follow-up period.The Visual Analog Scale of Nasal Congestion(VAS),the Nasal Resistive Index(NRI),the Nasal Acoustic Reflex(NAR),and the sinuses outcome test-20(SNOT-20)were compared and analyzed before and after treatment for the two groups.Results The total effective rate of treatment in the Chinese medicine flushing group(92.7%)was higher than that in the saline flushing group(76.2%),and the difference was statistically significant(P<0.05);the rate of decongestant reuse in the Chinese medicine flushing group(7.7%)was lower than that of decongestant reuse in the saline flushing group(28.1%)and the difference was statistically significant(P<0.05);Compared with before treatment,VAS score,SNOT-20 score and effective resistance of nasal cavity decreased(P<0.05),and nasal cavity volume increased significantly(P<0.05).The VAS score of nasal obstruction,nasal effective resistance and nasal volume 0-7cm from nostril were not significantly different between the two groups before treatment(P>0.05).After treatment,the VAS score of nasal obstruction,the SNOT-20 score,nasal effective resistance in the Chinese medicine irrigation group were significantly lower than those in the saline irrigation group(P<0.05),and nasal volume 0-7cm from nostril in the Chinese medicine irrigation group was significantly higher than that in the saline irrigation group(P<0.05).Conclusion Jiawei Yupingfeng nasal irrigation combined with nasal corticosteroids therapy is better than saline nasal irrigation combined with Nasal corticosteroids therapy,which significantly reduced the patients'dependence on decongestants and significantly improved their quality of life.关键词
加味玉屏风散/药物性鼻炎/鼻腔冲洗/鼻用皮质类固醇/肺脾气虚证Key words
Jiawei Yupingfeng/rhinitis medicamentosa/nasal irrigation/nasal corticosteroids引用本文复制引用
王晓瑞,夏睿琪,刘怡陶,吴莹莹,陈慧,冯炜..鼻用皮质类固醇联合中药鼻腔冲洗治疗肺脾气虚型药物性鼻炎的疗效观察[J].北京中医药,2026,45(1):16-21,6.基金项目
中国中医科学院科技创新工程重大攻关项目(CI2021A02704) （CI2021A02704）
