结直肠肛门外科2026，Vol.32Issue(1)：90-95,6.DOI:10.19668/j.cnki.issn1674-0491.2026.01.013
直肠癌根治术后吻合口漏的发生情况及其影响因素分析:基于1064例患者的临床资料
Incidence and influencing factors of anastomotic leakage after radical resection of rectal cancer:an analysis based on clinical data from 1,064 patients
摘要
Abstract
Objectives To analyze the incidence and influencing factors of anastomotic leakage(AL)after radical resec-tion of rectal cancer.Methods Clinical data from 1,064 patients who underwent laparoscopy-assisted or robot-assisted radical resection of rectal cancer in the Northern Jiangsu People's Hospital,Clinical Teaching Hospital of Medical School,Nanjing University,from January 2018 to January 2024 were retrospectively analyzed.The incidence of postoperative AL was calculated,and patients were divided into a non-AL group and an AL group based on the occurrence of AL.Clinical data(including general characteristics,tumor status,and clinical treatment details)were recorded and compared between the two groups.Results Among the 1,064 patients,50 developed postoperative AL,resulting in an incidence rate of 4.7%.Compared to the non-AL group,the AL group had significantly higher proportions of patients with body mass in-dex(BMI)≥25 kg/m²,a history of diabetes mellitus,undergoing laparoscopy-assisted surgery,non-preservation of the left colic artery(LCA),not using indocyanine green fluorescence imaging(ICG-FI)to assess anastomotic blood supply,and not performing reinforcing sutures at the anastomosis(P＜0.05).No statistically significant differences were found be-tween the two groups regarding age distribution,sex,smoking history,alcohol consumption history,receipt of neoadju-vant therapy,preoperative T stage,preoperative N stage,tumor size distribution,operation time distribution,intraopera-tive blood loss distribution,lateral lymph node dissection,number of stapler cartridges used,or placement of transanal tube(P＞0.05).Conclusion In patients undergoing laparoscopy-assisted or robot-assisted radical resection of rectal cancer,those with BMI≥25 kg/m² and a history of diabetes mellitus have a relatively higher likelihood of developing postopera-tive AL.Furthermore,undergoing laparoscopy-assisted surgery,non-preservation of the LCA,not using ICG-FI to assess anas-tomotic blood supply,and not performing reinforcing sutures at the anastomosis may increase the risk of postoperative AL.关键词
直肠癌/吻合口漏/影响因素/腹腔镜辅助手术/机器人辅助手术Key words
rectal cancer/anastomotic leakage/influencing factors/laparoscopy-assisted surgery/robot-assisted surgery分类
医药卫生引用本文复制引用
李瑞奇,王道荣..直肠癌根治术后吻合口漏的发生情况及其影响因素分析:基于1064例患者的临床资料[J].结直肠肛门外科,2026,32(1):90-95,6.基金项目
江苏省卫生健康委科研项目(ZD2022047) （ZD2022047）
