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甲状腺髓样癌术前系统性评估的"七步法"

周倩蕾 申宇昕 魏瑾晨 龙淼云

广东医学2026,Vol.47Issue(2):161-165,5.
广东医学2026,Vol.47Issue(2):161-165,5.DOI:10.13820/j.cnki.gdyx.20253608

甲状腺髓样癌术前系统性评估的"七步法"

The Seven-Step preoperative systematic assessment for medullary thyroid carcinoma

周倩蕾 1申宇昕 2魏瑾晨 1龙淼云1

作者信息

  • 1. 中山大学第六附属医院普通外科(甲状腺外科),广东省结直肠盆底疾病研究重点实验室,中山大学第六附属医院生物医学创新研究院(广东 广州 510510)
  • 2. 中山大学孙逸仙纪念医院甲状腺外科(广东 广州 510120)
  • 折叠

摘要

Abstract

Medullary thyroid carcinoma(MTC)is a neuroendocrine malignancy characterized by a relatively poor prognosis,a high propensity for early metastasis,and limited sensitivity to conventional chemotherapy and radiotherapy.Clinical outcomes largely depend on the completeness of the initial surgical intervention.Based on the pathophysiological and clinical characteristics of MTC,this review proposes a structured"seven-step"preoperative assessment strategy.This systematic approach integrates biochemical e-valuation,pathological confirmation,imaging-based staging,genetic screening,assessment of coexisting conditions,surgical plan-ning,and perioperative risk stratification.The aim is to address current gaps in diagnosis and management through precise initial treat-ment,thereby providing clinicians with a comprehensive and orderly assessment framework to guide radical tumor resection,minimize the need for reoperation,and ultimately improve patient prognosis.

关键词

甲状腺髓样癌/病理确诊/遗传筛查/初始治疗/手术规划

Key words

medullary thyroid carcinoma/pathological confirmation/genetic screening/initial treatment/surgical planning

分类

医药卫生

引用本文复制引用

周倩蕾,申宇昕,魏瑾晨,龙淼云..甲状腺髓样癌术前系统性评估的"七步法"[J].广东医学,2026,47(2):161-165,5.

广东医学

1001-9448

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