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MARCH2 suppresses odontoblast differentiation by polyubiquitinating PTPRD

Hao Feng Jiaxin Niu Zhi Chen Guobin Yang Guohua Yuan

国际口腔科学杂志（英文版）2026，Vol.18Issue(1)：126-136,11.

国际口腔科学杂志（英文版）2026，Vol.18Issue(1)：126-136,11.DOI:10.1038/s41368-025-00407-2

MARCH2 suppresses odontoblast differentiation by polyubiquitinating PTPRD

Hao Feng ¹Jiaxin Niu ¹Zhi Chen ²Guobin Yang ²Guohua Yuan¹

作者信息

1. State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration,Key Laboratory of Oral Biomedicine Ministry of Education,Hubei Key Laboratory of Stomatology,School & Hospital of Stomatology,Wuhan University,Wuhan,China||Frontier Science Center for Immunology and Metabolism,Wuhan University,Wuhan,China||Hubei Provincial Key Laboratory of Developmentally Originated Disease,Wuhan University,Wuhan,China
2. State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration,Key Laboratory of Oral Biomedicine Ministry of Education,Hubei Key Laboratory of Stomatology,School & Hospital of Stomatology,Wuhan University,Wuhan,China
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Hao Feng,Jiaxin Niu,Zhi Chen,Guobin Yang,Guohua Yuan..MARCH2 suppresses odontoblast differentiation by polyubiquitinating PTPRD[J].国际口腔科学杂志（英文版）,2026,18(1):126-136,11.

基金项目

This work was supported by grants from the National Natural Science Foundation of China(82370913,82170914 to Guohua Yuan and 82270947 to Guobin Yang) （82370913,82170914 to Guohua Yuan and 82270947 to Guobin Yang）

the National Natural Science Foundation of China Key Program(82230029 to Z.C) （82230029 to Z.C）

the Fundamental Research Funds for the Central Universities(2042022dx0003),and the Innovation Project of Municipal Science and Technology Bureau(2023020201010170)to Guohua Yuan.We thank Prof.Hong-bing Shu from Wuhan University for providing the March2 deficient mice.We thank Prof.Baoli Wang from Tianjin Medical University for providing the Ptprd plasmid. （2042022dx0003）

国际口腔科学杂志（英文版）

ISSN：1674-2818

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