国际口腔科学杂志（英文版）2026，Vol.18Issue(1)：137-151,15.DOI:10.1038/s41368-025-00406-3
Wnt3a promotes in situ dentin formation through NKD1-MSX1 axis-mediated odontogenic differentiation of dental pulp stem cells
Wnt3a promotes in situ dentin formation through NKD1-MSX1 axis-mediated odontogenic differentiation of dental pulp stem cells
Haoran Du 1Jianguang Xu 2Jingsong Wang 3Hideaki Kagami 4Xianqi Li 5Su Chen 6Jian Zhou 7Qiong Li 8Chenchen Zhou 9Junji Xu 10Kang Gao 1Zixiao Li 1Yifan Xu 11Ousheng Liu 12Bing Li13
作者信息
- 1. Department of International Medical Center,Beijing Stomatological Hospital,Capital Medical University,Beijing,China||Beijing Laboratory of Oral Health,Capital Medical University,Beijing,China
- 2. College & Hospital of Stomatology,Key Laboratory of Oral Diseases Research of Anhui Province,Anhui Medical University,Hefei,Anhui,China
- 3. Beijing Laboratory of Oral Health,Capital Medical University,Beijing,China
- 4. Department of Dentistry and Oral and Surgery,Aichi Medical University,Nagakute,Aichi,Japan
- 5. Department of Oral and Maxillofacial Surgery,School of Dentistry,Matsumoto Dental University,Shiojiri,Japan
- 6. Department of International Medical Center,Beijing Stomatological Hospital,Capital Medical University,Beijing,China
- 7. Department of International Medical Center,Beijing Stomatological Hospital,Capital Medical University,Beijing,China||Beijing Laboratory of Oral Health,Capital Medical University,Beijing,China||Laboratory for Clinical Medicine,Capital Medical University,Beijing,China||Laboratory for Oral and General Health Integration and Translation,Beijing Tian tan Hospital,Capital Medical University,Beijing,China
- 8. Beijing Laboratory of Oral Health,Capital Medical University,Beijing,China||Laboratory of Tissue Regeneration and Immunology and Department of Periodontics,Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction,School of Stomatology,Capital Medical University,Beijing,China||Laboratory for Clinical Medicine,Capital Medical University,Beijing,China
- 9. State Key Laboratory of Oral Diseases & National Clinical Research Centre for Oral Diseases & Department of Pediatric Dentistry,West China Hospital of Stomatology,Sichuan University,Chengdu,Sichuan,China
- 10. College of Stomatology,Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences,Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education,Chongqing Medical University,Chongqing,China
- 11. Beijing Laboratory of Oral Health,Capital Medical University,Beijing,China||Laboratory for Clinical Medicine,Capital Medical University,Beijing,China
- 12. Xiangya Stomatological Hospital,Central South University,Changsha,Hunan,China
- 13. School and Hospital of Stomatology,Shanxi Medical University,Taiyuan,Shanxi,China
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Haoran Du,Jianguang Xu,Jingsong Wang,Hideaki Kagami,Xianqi Li,Su Chen,Jian Zhou,Qiong Li,Chenchen Zhou,Junji Xu,Kang Gao,Zixiao Li,Yifan Xu,Ousheng Liu,Bing Li..Wnt3a promotes in situ dentin formation through NKD1-MSX1 axis-mediated odontogenic differentiation of dental pulp stem cells[J].国际口腔科学杂志（英文版）,2026,18(1):137-151,15.基金项目
This work was supported by the National Natural Science Foundation of China(82170951,82470961) （82170951,82470961）
the Beijing Natural Science Foundation(7222079) （7222079）
the Beijing Hospital Authority"Dengfeng"Talent Training Plan(DFL 20221301) （DFL 20221301）
the Beijing Stomatological Hospital,Capital Medical University Young Scientist Program(No.YSP202401).The authors gratefully acknowledge the Laboratory for Clinical Medicine and the Central Laboratory of Capital Medical University for their technical support and funding.We also thank the Japan China Sasakawa Medical Fellowship for their generous support and funding. （No.YSP202401）
