基层中医药2026，Vol.5Issue(2)：70-75,6.DOI:10.20065/j.cnki.btcm.20260050
复方四黄外洗剂联合封闭负压间歇灌洗技术治疗糖尿病足感染伤口的疗效观察
Observation on Efficacy of Compound Sihuang External Lotion Combined with Closed Negative Pressure Intermittent Lavage Technique in Treatment of Infected Wounds of Diabetic Feet
摘要
Abstract
Objective This paper aims to observe the clinical efficacy of Compound Sihuang External Lotion combined with the closed negative pressure intermittent lavage technique in the treatment of infected wounds of diabetic feet.Methods A total of 128 patients with infected wounds of diabetic feet who were treated in Zhongshan Traditional Chinese Medicine Hospital from June 2023 to September 2024 were selected and divided into the observation group(64 cases)and the control group(64 cases)based on the random number table method.The control group was treated with negative pressure saline lavage,and the observation group was treated with Compound Sihuang External Lotion combined with closed negative pressure intermittent lavage.After the same treatment time,the clinical efficacy,laboratory test indicators(procalcitonin(PCT),interleukin-6(IL-6),C-reactive protein(CRP),and white blood cell(WBC)),local symptom scores of diabetic feet,and traditional Chinese medicine syndrome score of the two groups were compared.Results The clinical efficacy of the observation group was significantly better than that of the control group(P<0.05).Before treatment,there was no statistically significant difference between the two groups in laboratory test indicators,local symptom scores of diabetic feet,and traditional Chinese medicine syndrome scores(P>0.05).After two weeks and four weeks of treatment,the observation group showed greater improvements in PCT,IL-6,CRP,and WBC levels compared to the control group(P<0.05),and the local symptoms of diabetic feet and traditional Chinese medicine syndrome scores were significantly lower in the observation group than those in the control group(P<0.05).Conclusion The clinical efficacy of Compound Sihuang External Lotion combined with the closed negative pressure intermittent lavage technique in the treatment of infected wounds of diabetic feet is significantly better than that of negative pressure saline lavage treatment,which can effectively improve laboratory test indicators and local symptoms of diabetic feet.关键词
复方四黄外洗剂/封闭负压间歇灌洗/糖尿病足Key words
Compound Sihuang External Lotion/closed negative pressure intermittent lavage/diabetic foot引用本文复制引用
李文华,黄金梅,蔡小敏..复方四黄外洗剂联合封闭负压间歇灌洗技术治疗糖尿病足感染伤口的疗效观察[J].基层中医药,2026,5(2):70-75,6.基金项目
中山市医学科研项目(2023A020322) （2023A020322）
