摘要
Abstract
Objective To explore the clinical effect of goal-directed analgesia and sedation strategy in neurosurgical critical patients,and to explore the effect of this method on the prognosis of patients.Methods A total of 86 neurosurgical intensive care patients admitted to the Third Affiliated Hospital of Zunyi Medical University from January 2024 to April 2025 were selected as the study subjects.They were divided into control group and study group using random number table method,with 43 patients in each group.The control group received conventional analgesia and sedation,while the study group received goal-directed analgesia and sedation strategy.Clinical indicators,vital signs,analgesic and sedative effects,cerebral function,Glasgow coma scale(GCS)scores,and the incidence of complications were compared between the two groups.Results The mechanical ventilation time and ICU stay time of the study group were shorter than those of the control group,and the differences were statistically significant(P＜0.05).After treatment,the heart rate(HR)and respiratory rate(RR)in the study group were lower than those in the control group,and the oxygenation index(PaO2/FiO2)level was higher than that in the control group,and the differences were statistically significant(P＜0.05).After treatment,the visual ana-logue scale(VAS)and Ramsay sedation score of the study group were lower than those of the control group,and the differences were statistically significant(P＜0.05).After treatment,the delirium rating scale(DRS)score of the study group was lower than that of the control group,and the GCS score was higher than that of the control group,and the differences were statistically significant(P＜0.05).The total incidence of complications in the study group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion In the treatment of neurosurgical inten-sive care unit,the implementation of goal-directed analgesia and sedation strategy can improve the analgesic and sedative effects of patients,effectively reduce the incidence of complications,and show its outstanding clinical value and help to improve the prognosis of patients.关键词
目标导向镇痛镇静策略/神经外科重症/临床应用/预后Key words
Goal-directed analgesia and sedation strategy/Neurosurgical intensive care/Clinical application/Prognosis分类
医药卫生
