神经病学与神经康复学杂志2026，Vol.22Issue(1)：34-37,4.DOI:10.12022/jnnr.2025-0088
抗幽门螺杆菌治疗后出现吉兰-巴雷综合征:1例报告及文献复习
Guillain-Barre syndrome after anti-Helicobacter pylori treatment:A case report and literature review
裘冯卓 1潘宜久 2王连魁2
作者信息
- 1. 宁波市杭州湾医院暨上海交通大学医学院附属仁济医院宁波医院神经内科,浙江 宁波 315300
- 2. 宁波市杭州湾医院暨上海交通大学医学院附属仁济医院宁波医院消化内科,浙江 宁波 315300
- 折叠
摘要
Abstract
Objective:To enhance the clinical understanding of the correlation between Helicobacter pylori(Hp)and Guillain-Barre syndrome(GBS).
Methods:This paper reports the clinical diagnosis and treatment process of a patient with GBS caused by Hp infection.Combined with literature review,the correlation between Hp and GBS is mainly explored.
Results:The patient had an acute onset and a history of Hp infection.The initial manifestation was gastrointestinal symptoms,which gradually worsen,leading to symmetrical weakness in both lower limbs and weakened tendon reflexes.Cerebrospinal fluid examination revealed protein-cell dissociation.Electrophysiological examination indicated demyelinating changes in peripheral nerves,manifested as prolonged distal motor nerve conduction latency,slowed conduction velocity,abnormal F-waves,conduction block and waveform dispersion.The patient was ultimately diagnosed with GBS.After standard immunotherapy,the patient had a good prognosis.
Conclusion:For the acute occurrence of digestive symptoms and peripheral nervous system-related symptoms in patients with Hp infection,it is particularly important in clinical practice to identify early whether GBS is induced by Hp infection,in order to achieve early diagnosis and early treatment and improve the prognosis of patients.关键词
吉兰-巴雷综合征/幽门螺杆菌/诊断/治疗Key words
Guillain-Barre syndrome/Helicobacter pylori/Diagnosis/Treatment引用本文复制引用
裘冯卓,潘宜久,王连魁..抗幽门螺杆菌治疗后出现吉兰-巴雷综合征:1例报告及文献复习[J].神经病学与神经康复学杂志,2026,22(1):34-37,4.
