神经病学与神经康复学杂志2026，Vol.22Issue(1)：55-64,10.DOI:10.12022/jnnr.2025-0280
脊髓性肌萎缩康复治疗进展
Advances in rehabilitation of spinal muscular atrophy
摘要
Abstract
Spinal muscular atrophy(SMA)is an autosomal recessive neuromuscular disorder whose rehabilitation requires individualized strategies based on disease subtype and functional impairment.This review systematically summarizes recent advances in the assessment and rehabilitation of respiratory,motor and swallowing dysfunctions in patients with SMA.For respiratory dysfunction,the techniques such as pulmonary function tests,diaphragmatic ultrasound and sleep monitoring,along with interventions including non-invasive ventilation,were evaluated.For motor function,various assessment tools such as functional scales,muscle ultrasound and physical fitness tests were summarized.Additionally,rehabilitation strategies for patients with different motor abilities were analyzed,including strength training,robot-assisted training and neuromodulation techniques.For swallowing function,the assessment methods such as videofluoroscopic swallowing examination,fiberoptic endoscopic evaluation of swallowing and oral pressure measurement,as well as therapeutic approaches including functional training and compensatory strategies,were examined.This review aims to provide an evidence-based framework for rehabilitation and suggests that future research should focus on the clinical translation of multimodal biomarkers and home-based rehabilitation technology to optimize the outcomes and enhance the quality of life.关键词
脊髓性肌萎缩/康复评定/康复治疗/功能障碍Key words
Spinal muscular atrophy/Rehabilitation assessment/Rehabilitation therapy/Dysfunction引用本文复制引用
倪珏皓,兰丹梅,洪荣华,靳令经..脊髓性肌萎缩康复治疗进展[J].神经病学与神经康复学杂志,2026,22(1):55-64,10.基金项目
国家临床重点专科建设项目(Z155080000004) （Z155080000004）
上海市康复医学重中之重研究中心(2023ZZ02027) （2023ZZ02027）
上海市级医院示范性研究型病房(SHDC2023CRW 018B) （SHDC2023CRW 018B）
上海市级医院诊疗技术推广及优化管理项目(SHDC22023304) National Clinical Key Specialty Construction Project(Z155080000004) （SHDC22023304）
Shanghai Key Laboratory of Rehabilitation Medicine(2023ZZ02027) （2023ZZ02027）
Shanghai Municipal Hospital Demonstrative Research-Oriented Ward(SHDC2023CRW018B) （SHDC2023CRW018B）
Shanghai Municipal Hospital Diagnosis and Treatment Technology Promotion and Optimization Management Project(SHDC22023304) （SHDC22023304）
