实用心脑肺血管病杂志2026，Vol.34Issue(5)：22-25,4.DOI:10.12114/j.issn.1008-5971.2026.00.104
踝肱指数与老年高血压患者发生心脑血管死亡的关系研究
Relationship between Ankle-Brachial Index and Incidence of Cardio-Cerebrovascular Death in Elderly Hypertensive Patients
摘要
Abstract
Objective To investigate the relationship between ankle-brachial index(ABI)and incidence of cardio-cerebrovascular death in elderly hypertensive patients.Methods A total of 1 202 patients with hypertension who received treatment at Mianyang Central Hospital from March to June 2021 were selected as the study participants.Clinical data of the patients were collected.After 3 years of follow-up,patients were divided into the cardio-cerebrovascular death group and the non-cardio-cerebrovascular death group according to the occurrence of cardio-cerebrovascular death.Generalized additive model was used to analyze the correlation between ABI and the risk of cardio-cerebrovascular death in elderly hypertensive patients,and multivariate Cox proportional hazards regression analysis was used to analyze the relationship between ABI and the risk of cardio-cerebrovascular death in elderly hypertensive patients.Results After 3 years of follow-up,516 patients with missing ABI data and 6 patients lost to follow-up were excluded,ultimately 680 patients were enrolled.Among the 680 patients,43 cases(6.32%)happened cardio-cerebrovascular death.The smoking rate,drinking rate,proportion of patients with chronic kidney disease in the cardio-cerebrovascular death group were higher than those in the non-cardio-cerebrovascular death group,triglyceride,low-density lipoprotein cholesterol,and ABI were lower than those in the non-cardio-cerebrovascular death group(P<0.05).Generalized additive model analysis results revealed that ABI exhibited a"L"-shaped nonlinear correlation with cardio-cerebrovascular death in elderly hypertensive patients(P for overall=0.023,P for nonlinear=0.005),and with the lowest inflection point at 1.16.Multivariate Cox proportional hazards regression analysis results showed that ABI<1.16 was an independent risk factor for cardio-cerebrovascular death in elderly hypertensive patients(P<0.001).Conclusion ABI exhibits a"L"-shaped nonlinear correlation with cardio-cerebrovascular death in elderly hypertensive patients,and ABI<1.16 is an independent risk factor for cardio-cerebrovascular death in patients with hypertension.关键词
高血压/老年人/踝肱指数/心脑血管死亡Key words
Hypertension/Aged/Ankle-brachial index/Cardio-cerebrovascular death分类
医药卫生引用本文复制引用
周惠,黄莉莉,刘洋鸣..踝肱指数与老年高血压患者发生心脑血管死亡的关系研究[J].实用心脑肺血管病杂志,2026,34(5):22-25,4.基金项目
2024年医疗质量(循证)管理研究项目(YLZLXZ24G088) （循证）
