实用心脑肺血管病杂志2026，Vol.34Issue(5)：26-30,5.DOI:10.12114/j.issn.1008-5971.2026.00.099
尿酸与白蛋白比值与高血压患者合并左心室肥厚的关系研究
Relationship between Uric Acid to Albumin Ratio and Left Ventricular Hypertrophy in Patients with Hypertension
摘要
Abstract
Objective To investigate the relationship between uric acid to albumin ratio(UAR)and left ventricular hypertrophy in patients with hypertension.Methods A total of 438 patients with hypertension admitted to the First Affiliated Hospital of Anhui Medical University from September 2021 to January 2025 were retrospectively selected as the research subjects.The clinical data of the patients were collected,and the patients were divided into hypertrophy group(n=158),and non-hypertrophy group(n=280)according to the presence of left ventricular hypertrophy[left ventricular mass index(LVMI)≥109 g/m2 for males or LVMI≥105 g/m2 for females].Spearman rank correlation analysis was used to explore the correlation between UAR and LVMI in patients with hypertension.Univariate and multivariate Logistic regression analysis was used to explore the influencing factors.Results The age in the hypertrophy group was older than that in the non-hypertrophy group,systolic blood pressure,pulse pressure,proportion of patients with hypertension duration≥10 years,serum creatinine,uric acid,fasting blood glucose,and UAR were higher than those in the non-hypertrophy group,albumin was lower than that in the non-hypertrophy group(P<0.05).Spearman rank correlation analysis showed that there was a positive correlation between UAR and LVMI in patients with hypertension(rs=0.275,P<0.001).Univariate Logistic regression analysis showed that age,systolic blood pressure,pulse pressure,hypertension duration,serum creatinine,fasting blood glucose,and UAR may be influencing factors of left ventricular hypertrophy in patients with hypertension(P<0.05).Multivariate Logistic regression analysis showed that pulse pressure,hypertension duration,and UAR were independent influencing factors of left ventricular hypertrophy in patients with hypertension(P<0.05).Conclusion There is a positive correlation between UAR and LVMI in patients with hypertension,and UAR is an independent influencing factor of left ventricular hypertrophy in patients with hypertension.关键词
高血压/肥大,左心室/尿酸与白蛋白比值Key words
Hypertension/Hypertrophy,left ventricular/Uric acid to albumin ratio分类
医药卫生引用本文复制引用
宋昕,陆红红,周碧蓉..尿酸与白蛋白比值与高血压患者合并左心室肥厚的关系研究[J].实用心脑肺血管病杂志,2026,34(5):26-30,5.基金项目
安徽省卫健委适宜技术推广项目(2018-TG03) （2018-TG03）
安徽省学术技术带头人科研活动项目(2021D279) （2021D279）
