时珍国医国药2026,Vol.37Issue(6):1124-1130,7.DOI:10.70976/j.1008-0805.SZGYGY-2026-0618
子宫内膜异位症免疫因素及中药治疗的研究进展
Research progress on immune factors and Chinese herbal medicine treatment of endometriosis
摘要
Abstract
Immune dysregulation within the microenvironment of ectopic lesions is a major contributing factor to endometriosis(EM).In recent years,numerous studies have investigated the therapeutic effects of Chinese medicinals(CMs)on EM through multi-level interventions,including the regulation of immune cell and complement system functions,as well as cytokine and antibody levels.Numerous randomized controlled trials have demonstrated that CMs can modulate immune system function,enhance host defense,allevi-ate inflammation,and consequently inhibit the implantation and invasion of ectopic EM.This review aims to comprehensively summa-rize Chinese herbal compounds,active monomers,and extracts that modulate immune responses in EM,analyze their specific mecha-nisms and the findings from randomized controlled trials(RCTs),identify current research gaps,and propose potential new clinical strategies for managing this condition.关键词
子宫内膜异位症/中药/免疫失调/Th17/Treg平衡/巨噬细胞/补体系统/抗体/炎症因子Key words
Endometriosis/Chinese herbal medicine/Immune dysfunction/Th17/Treg balance/Macrophage/Complement system/Antibody/Inflammatory factors分类
医药卫生引用本文复制引用
孙昕玮,贾志诚,李永谦,王培璇,石梦雨,杨鑫鑫,亓文隆,郭颖..子宫内膜异位症免疫因素及中药治疗的研究进展[J].时珍国医国药,2026,37(6):1124-1130,7.基金项目
国家自然科学基金面上项目(82374505) (82374505)
山东省自然科学基金面上项目(ZR2023MH219) (ZR2023MH219)
济南市科技发展计划(202225005) (202225005)
泰山学者青年专家项目(202211353) (202211353)