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子宫内膜异位症免疫因素及中药治疗的研究进展

孙昕玮 贾志诚 李永谦 王培璇 石梦雨 杨鑫鑫 亓文隆 郭颖

时珍国医国药2026,Vol.37Issue(6):1124-1130,7.
时珍国医国药2026,Vol.37Issue(6):1124-1130,7.DOI:10.70976/j.1008-0805.SZGYGY-2026-0618

子宫内膜异位症免疫因素及中药治疗的研究进展

Research progress on immune factors and Chinese herbal medicine treatment of endometriosis

孙昕玮 1贾志诚 2李永谦 1王培璇 1石梦雨 1杨鑫鑫 1亓文隆 1郭颖3

作者信息

  • 1. 山东中医药大学第一临床医学院,山东 济南 250014
  • 2. 中国中医科学院广安门医院,北京 100053
  • 3. 山东中医药大学第一临床医学院,山东 济南 250014||山东中医药大学中医学院,山东 济南 250014||山东中医药大学附属医院生殖与遗传中心,山东 济南 250011
  • 折叠

摘要

Abstract

Immune dysregulation within the microenvironment of ectopic lesions is a major contributing factor to endometriosis(EM).In recent years,numerous studies have investigated the therapeutic effects of Chinese medicinals(CMs)on EM through multi-level interventions,including the regulation of immune cell and complement system functions,as well as cytokine and antibody levels.Numerous randomized controlled trials have demonstrated that CMs can modulate immune system function,enhance host defense,allevi-ate inflammation,and consequently inhibit the implantation and invasion of ectopic EM.This review aims to comprehensively summa-rize Chinese herbal compounds,active monomers,and extracts that modulate immune responses in EM,analyze their specific mecha-nisms and the findings from randomized controlled trials(RCTs),identify current research gaps,and propose potential new clinical strategies for managing this condition.

关键词

子宫内膜异位症/中药/免疫失调/Th17/Treg平衡/巨噬细胞/补体系统/抗体/炎症因子

Key words

Endometriosis/Chinese herbal medicine/Immune dysfunction/Th17/Treg balance/Macrophage/Complement system/Antibody/Inflammatory factors

分类

医药卫生

引用本文复制引用

孙昕玮,贾志诚,李永谦,王培璇,石梦雨,杨鑫鑫,亓文隆,郭颖..子宫内膜异位症免疫因素及中药治疗的研究进展[J].时珍国医国药,2026,37(6):1124-1130,7.

基金项目

国家自然科学基金面上项目(82374505) (82374505)

山东省自然科学基金面上项目(ZR2023MH219) (ZR2023MH219)

济南市科技发展计划(202225005) (202225005)

泰山学者青年专家项目(202211353) (202211353)

时珍国医国药

1008-0805

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