物理化学学报2026，Vol.42Issue(2)：96-108,13.DOI:10.1016/j.actphy.2025.100134
源自绿萝叶提取物的红光碳点制备和生物成像应用
Red-emitting carbon dots prepared from Epipremnum Aureum leaves extract for biological imaging
摘要
Abstract
Carbon dots(CDs)have been widely applied in fluorescence imaging both in vitro and in vivo.However,key challenges remain to be addressed,including the poor specificity of CDs as biological markers and their relatively low fluorescence quantum yield(QY)in the red emission region.In this study,we synthesized red fluorescent carbon dots(designated as EA-CDs,λex/λem=400 nm/660 nm)using a natural plant-derived precursor ethanol extract from Epipremnum aureum leaves via a one-pot solvothermal method.The EA-CDs exhibit a small particle size(average diameter:3.9 nm),high fluorescence QY(15.4%in ethanol at λem=660 nm),low toxicity(both in vitro and in vivo),and favorable lipophilicity(oil-water partition coefficient LogP>0),making them suitable for biological fluorescence imaging and labeling applications.Experimental results indicate that these red-emitting CDs can not only effectively label plant cell membranes,but also serve as an intestinal fluorescence imaging probe in zebrafish models.This suggests their potential as a universal red-emissive bio-membrane dye with high QY.Furthermore,this work pioneers a novel application approach for ornamental plants like Epipremnum aureum.关键词
碳点/红光发射/生物成像/膜染料/绿萝/斑马鱼Key words
Carbon dots/Red emission/Biological imaging/Membrane dyes/Epipremnum aureum/Zebrafish分类
化学化工引用本文复制引用
邵仁义,库拉姆·阿巴斯,弗拉基米尔·尤里耶维奇·奥西波夫,朱海梅,李远,乌萨马,毕红..源自绿萝叶提取物的红光碳点制备和生物成像应用[J].物理化学学报,2026,42(2):96-108,13.基金项目
国家自然科学基金(52172033)及国家重点研发计划(2021YFA1600202)资助 （52172033）
