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西部少数民族地区HIV感染合并肺结核患者预后的临床与社会学分析

雷俊杰 沈小英 李昌敏 吉以也布 胡攀志 杨发平 何浩岚 刘新华

中国感染控制杂志2026,Vol.25Issue(3):352-356,5.
中国感染控制杂志2026,Vol.25Issue(3):352-356,5.DOI:10.12138/j.issn.1671-9638.20263013

西部少数民族地区HIV感染合并肺结核患者预后的临床与社会学分析

Clinical and sociological analysis of patients with human immunodeficiency virus infection complicated with pulmonary tuberculosis in western ethnic minority area

雷俊杰 1沈小英 1李昌敏 1吉以也布 1胡攀志 1杨发平 1何浩岚 2刘新华2

作者信息

  • 1. 四川省凉山彝族自治州昭觉县人民医院感染科,四川 凉山 615000
  • 2. 广州医科大学附属市八医院感染病中心,广东 广州 510440
  • 折叠

摘要

Abstract

Objective To explore the clinical and sociological characteristics of patients with human immunodefi-ciency virus(HIV)infection complicated with pulmonary tuberculosis(PTB)in western ethnic minority area,analyze the risk factors affecting their prognosis,and provide basis for developing comprehensive prevention and intervention strategies in resource-limited areas.Methods 126 patients with HIV-PTB co-infection admitted to a people's hospital in a western ethnic minority area from January 2022 to December 2023 were included in analysis retrospectively.Demographic,clinical,laboratory,imaging,and sociological data(education level,marital status,transportation accessibility,economic status)of patients were collected,and the differences between good prognosis group and poor prognosis group were compared,independent risk factors for the prognosis were analyzed by multi-variate logistic regression.Results Among the 126 patients,77.0%were male,with an average age of(40.3±9.2)years old.Multivariate logistic regression analysis showed that CD4+T lymphocyte cells<200 cells/μL(OR=8.59,95%CI:3.31-22.29),bilateral lung lesions(OR=6.23,95%CI:2.57-15.07),non-standard anti-tuberculosis treatment(OR=5.89,95%CI:2.62-13.22),and low education level(OR=3.65,95%CI:1.54-8.65)were independent risk factors for poor prognosis.Conclusion The prognosis of patients with HIV-PTB co-infection is not only affected by clinical factors,but also closely related to sociological characteristics.Improving treatment compliance,strengthening community support,and enhancing health education levels are of great signifi-cance for improving the prognosis of patients with HIV-PTB co-infection in remote ethnic minority area.

关键词

HIV/AIDS/结核病/双重感染/预后/社会学因素/少数民族地区

Key words

HIV/AIDS/tuberculosis/dual infection/prognosis/sociological factor/ethnic minority area

分类

医药卫生

引用本文复制引用

雷俊杰,沈小英,李昌敏,吉以也布,胡攀志,杨发平,何浩岚,刘新华..西部少数民族地区HIV感染合并肺结核患者预后的临床与社会学分析[J].中国感染控制杂志,2026,25(3):352-356,5.

基金项目

广州市科技计划项目(2024A03J0874) (2024A03J0874)

中国性病艾滋病防治协会凉山州"三线一网底"能力建设开放式小额资助项目(LS2024OR03) (LS2024OR03)

中国感染控制杂志

1671-9638

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