中国感染控制杂志2026，Vol.25Issue(3)：385-393,9.DOI:10.12138/j.issn.1671-9638.20267406
儿童ICU耳念珠菌医院感染聚集调查及基于HFMEA的防控策略研究
Cluster of Candida auris healthcare-associated infection in a pediatric intensive care unit as well as prevention and control strategies based on HFMEA
摘要
Abstract
Objective To investigate the cluster of Candida auris(C.auris)healthcare-associated infection(HAI)in a pediatric intensive care unit(PICU),clarify its transmission mechanism,identify prevention and control loopholes,and develop precise prevention and control strategies,so as to provide evidence-based support for the prevention and control of C.auris infection in children.Methods Epidemiological investigation were conducted on two children from whom C.auris were detected.Surveillance on environmental hygiene and active screening on high-risk children were carried out.Potential failure modes were identified by healthcare failure mode and effect analysis(HFMEA),prevention and control strategies were developed and the effectiveness of implementation were assessed.Results C.auris were detected from one healthcare worker(HCW)'s hand and one high-risk child's groin swab.HFMEA identified 8 high-risk failure modes,including inadequate awareness of HCWs,missed admi-ssion screening,and non-standard hand hygiene.After implementing prevention and control strategies,key indica-tors improved significantly,including the qualified rate of environmental hygiene surveillance,implementation rate of isolation measures,compliance rate of hand hygiene,and pathogen detection rate(all P<0.05),with no new cases reported for 5 months.Conclusion Hand contact among HCWs is the key link in the transmission of C.auris in PICU.HFMEA can effectively identify risks and control transmission.The closed-loop management model(surveillance-risk assessment-precise intervention-effectiveness verification)established in this study can provide reference for the prevention and control of C.auris infection in children.关键词
耳念珠菌/儿童重症监护病房/医院感染防控/医疗失效模式与效应分析/闭环管理模型Key words
Candida auris/pediatric intensive care unit/healthcare-associated infection prevention and control/healthcare failure mode and effect analysis/closed-loop management model分类
医药卫生引用本文复制引用
胡亚倩,李星,包彧雯,孙杭,李蒨,薛圣凡,胡静..儿童ICU耳念珠菌医院感染聚集调查及基于HFMEA的防控策略研究[J].中国感染控制杂志,2026,25(3):385-393,9.基金项目
南京市卫生科技发展项目(GAX22282) （GAX22282）
