中国康复2026，Vol.41Issue(3)：131-136,6.DOI:10.3870/zgkf.2026.03.001
不同时序组合的经颅直流电刺激联合虚拟现实技术对脑卒中后上肢功能的影响
Efficacy of combined transcranial dtirect current stimulation and virtual reality therapy using different temporal se-quences on upper limb function after stroke
摘要
Abstract
Objective:To evaluate the therapeutic effects of transcranial direct current stimulation(tDCS)com-bined with virtual reality(VR)technology on upper limb motor dysfunction following stroke,using different tempo-ral sequences.Methods:This study selected 60 patients with hemiplegia due to stroke who were hospitalized at our hospital from January 2024 to December 2024.Using a random number table,they were randomly divided into ob-servation group 1,observation group 2,and a control group,with 20 cases in each group.All three groups received conventional rehabilitation treatment and were given the combined treatment of tDCS and VR technology.Observa-tion group 1 received VR therapy followed by tDCS therapy(VR-tDCS),observation group 2 received tDCS therapy followed immediately by VR therapy(tDCS-VR),and the control group received sham tDCS followed immediately by VR therapy(sham tDCS-VR).The same therapist administered the Fugl-Meyer Assessment Upper Extremity(FMA-UE),Motricity Index Upper Limb(MI-UL),and Modified Barthel Index(MBI)to all patients in the three groups before and after treatment.Electroencephalogram(EEG)analysis was performed on all patients in the three groups before and after treatment.Results:Following treatment,the FMA-UE,MI-UL,and MBI scores in all three gro-ups were significantly higher than pre-treatment levels(P＜0.01).Compared with the control group,the ob-servation groups had significantly increased scores on all measures(P＜0.05).Furthermore,observation group 2 showed significantly higher scores than obser-vation group 1(P＜0.05).EEG analysis before and af-ter treatment showed that the DAR and DTABR values in all three groups were significantly superior to pre-treatment levels(P＜0.01).Pairwise comparisons revealed that observation group 2 demonstrated the most favorable outcomes,followed by observation group 1,both of which sig-nificantly outperformed the control group(P＜0.05).Conclusion:Both standalone virtual reality therapy and com-bined virtual reality therapy with tDCS effectively improve upper limb function after stroke.However,clinically,se-quential treatment with tDCS-VR is recommended for more effective improvement of post-stroke upper limb func-tion.关键词
脑卒中/经颅直流电/不同时序组合/虚拟现实技术/上肢功能Key words
stroke/transcranial direct current stimulation/different temporal sequences/virtual reality technolo-gy/upper limb function分类
医药卫生引用本文复制引用
陈杰,张玉明,高玲,褚凤明,张莉,张明..不同时序组合的经颅直流电刺激联合虚拟现实技术对脑卒中后上肢功能的影响[J].中国康复,2026,41(3):131-136,6.基金项目
徐州市卫生健康委医学科技创新项目(XWKYHT20240064) （XWKYHT20240064）
徐州市科技局卫生健康面上项目(KC25081) （KC25081）
