中国神经再生研究（英文版）2026，Vol.21Issue(7)：2761-2771,11.DOI:10.4103/NRR.NRR-D-24-01546
Brain organoids and genome editing:A new era in understanding human brain development and disorders
Brain organoids and genome editing:A new era in understanding human brain development and disorders
Min Zhou 1Zhenzhou Li 2Huan Wang 3Zhengliang Gao 4Yuanqing Cao 5Ke Yue 6Wenyu Wu 1Yutong Xie 5Daiyu Hu 5Jingjing Zhao 1Fang Xu 7Jianrong Guo3
作者信息
- 1. Clinical Research Center for Mental Health,Mental Health Center Affiliated to School of Medicine(Shanghai Hongkou Mental Health Center),Shanghai University,Shanghai,China||Department of Anesthesiology and Perioperative Medicine,General Hospital of Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,China||Department of Anesthesiology,Gongli Hospital of Shanghai Pudong New Area,Shanghai,China
- 2. Department of Anesthesiology and Perioperative Medicine,General Hospital of Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,China
- 3. Department of Anesthesiology,Gongli Hospital of Shanghai Pudong New Area,Shanghai,China
- 4. Department of Anesthesiology,Gongli Hospital of Shanghai Pudong New Area,Shanghai,China||Fundamental Research Center,Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center),School of Medicine,Tongji University,Shanghai,China||China-Japan Friendship Medical Research Institute,School of Medicine,Shanghai University,Shanghai,China
- 5. Fundamental Research Center,Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center),School of Medicine,Tongji University,Shanghai,China||School of Basic Medicine,Medical Genetics and Cell Biology,Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,China
- 6. Clinical Research Center for Mental Health,Mental Health Center Affiliated to School of Medicine(Shanghai Hongkou Mental Health Center),Shanghai University,Shanghai,China||Department of Anesthesiology,Gongli Hospital of Shanghai Pudong New Area,Shanghai,China
- 7. School of Basic Medicine,Medical Genetics and Cell Biology,Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,China
- 折叠
摘要
关键词
brain disorder/brain organoid/CRISPR/Cas9/disease modeling/drug screening/genome editing/human brain development/lineage tracing/organoid modeling/stem cell differentiationKey words
brain disorder/brain organoid/CRISPR/Cas9/disease modeling/drug screening/genome editing/human brain development/lineage tracing/organoid modeling/stem cell differentiation引用本文复制引用
Min Zhou,Zhenzhou Li,Huan Wang,Zhengliang Gao,Yuanqing Cao,Ke Yue,Wenyu Wu,Yutong Xie,Daiyu Hu,Jingjing Zhao,Fang Xu,Jianrong Guo..Brain organoids and genome editing:A new era in understanding human brain development and disorders[J].中国神经再生研究（英文版）,2026,21(7):2761-2771,11.基金项目
This work was supported by the Special Project for Clinical Research of Shanghai Municipal Health Commission,No.202140403(to HW) （to HW）
Key Disciplines Group Construction Project of Pudong Health Bureau of Shanghai,No.PWZxq 2022-05(to JG) （to JG）
Natural Science Foundation of Ningxia Hui Autonomous Region,No.2024AAC05084(to ZL) （to ZL）
Ningxia Hui Autonomous Region Key Research and Development Program,No.2021BEG03084(to FX) （to FX）
and National Natural Science Foundation of China,Nos.32370895 and 32070862(both to ZG). （both to ZG）
