摘要
Abstract
Acorus tatarinowii Schott,as a traditional Chinese medicinal material,has a long history of medical use.In recent years,significant progress has been made in the research on its chemical composition,pharmacological effects,and toxicology.This paper sys-tematically reviews the chemical composition,multi-target pharmacological mechanisms,and current status of toxicological research on Acorus tatarinowii Schott,aiming to provide a scientific basis for its clinical rational application and quality standardization.Chemical composition analysis shows that the main active component of Acorus tatarinowii Schott is volatile oil,with the highest content of β-asa-rone,and it also contains various active substances such as flavonoids,alkaloids,and polysaccharides.Pharmacological research shows that Acorus tatarinowii Schott has significant neuroprotective effects and can improve cognitive function by regulating neurotransmitters,antioxidant,anti-inflammatory,and inhibiting cell apoptosis.Its cardiovascular protective effects involve inhibiting inflammatory respon-ses,promoting angiogenesis,and improving energy metabolism.In addition,Acorus tatarinowii Schott also has multiple pharmacological activities such as antimicrobial,antioxidant,anticancer,and immunomodulatory effects.Toxicological studies have shown that Acorus tatarinowii Schott has high safety in short-term use,but its main active component,β-asarone,has a certain dose-dependent toxicity,and further systematic assessment is needed to identify potential risks.Future research should focus on standardizing the composition,elucidating the material basis of pharmacological effects of Acorus tatarinowii Schott,and promoting the clinical translation,thereby advancing its rational application and development in the fields of nervous system and cardiovascular diseases.关键词
石菖蒲/挥发油/化学成分/药理作用/毒理学/分子机制Key words
Acorus tatarinowii Schott/Volatile oil/Chemical composition/Pharmacological effects/Toxicology/Molecular mechanism分类
医药卫生
