中国中药杂志2026，Vol.51Issue(6)：1545-1554,10.DOI:10.19540/j.cnki.cjcmm.20251103.301
基于"药辅合一"理念的固体颗粒协同稳定中药挥发油Pickering乳液调控机制研究进展
Advances in regulatory mechanism of solid particles synergistically stabilizing essential oil of TCM Pickering emulsion based on concept of"combination of medicines and excipients"
摘要
Abstract
The"combination of medicines and excipients"is a unique medication concept proposed in the field of pharmaceutics and therapeutics,showcasing the holistic thinking and clinical application wisdom of traditional Chinese medicine(TCM)compound medication.It is not only an important feature that distinguishes it from chemical drug preparations,but also one of the core advantages of TCM preparations.Pickering emulsions,as effective and ideal carriers,can utilize natural macromolecules with"combination of medicines and excipients"characteristics as solid particle emulsifiers to replace conventional surfactants,demonstrating remarkable efficacy in enhancing the stability of essential oils in TCM.Based on the framework of the"combination of medicines and excipients"concept,this study systematically explored the specific mechanisms underlying the solid particle types and stabilization systems of Pickering emulsions for essential oils from TCM,analyzed the factors influencing the stability of emulsions,and explored their potential application value,aiming to provide theoretical basis for promoting formulation development and clinical application of essential oils from TCM.关键词
中药挥发油/药辅合一/Pickering乳液/固体颗粒/稳定机制Key words
TCM essential oil/combination of medicines and excipients/Pickering emulsion/solid particles/stability mechanism引用本文复制引用
刘英,赖丽旋,胡恢权,孔佳文,万娜,杨明,陈世彬,伍振峰..基于"药辅合一"理念的固体颗粒协同稳定中药挥发油Pickering乳液调控机制研究进展[J].中国中药杂志,2026,51(6):1545-1554,10.基金项目
国家自然科学基金面上项目(82474091) （82474091）
江西省重点研发计划项目(20243BBI91013) （20243BBI91013）
江西省科学教育学会在校研究生课题(2025KXJYS016) （2025KXJYS016）
