中医杂志2026，Vol.67Issue(5)：477-481,5.DOI:10.13288/j.11-2166/r.2026.05.003
王晞星从"五脏致咳"辨治免疫检查点抑制剂相关性肺炎经验
WANG Xixing's Clinical Experience in Treating Immune Checkpoint Inhibitor-Related Pneumonitis Based on the Theory of"Cough Attributed to the Five Zang(脏)Organs"
摘要
Abstract
This paper summarizes Professor WANG Xixing's clinical experience in treating immune checkpoint inhibitor-related pneumonitis(CIP)based on the theory of"cough attributed to the five zang(脏)organs".Cough is a common predominant symptom of CIP.According to the theory of"cough attributed to the five zang organs",drug toxicity triggers cancer toxin,leading to disharmony among the five zang organs,and then lung failing to diffuse and govern descent as the core pathogenesis.Therefore,treatment should focus on harmonizing the five zang organs to restore the normal function of lung qi to diffuse and govern descent.In clinical practice,CIP can be classified into four syn-drome patterns,including lung yin depletion,deficiency of both the lung and the spleen with phlegm-dampness,liver fire harassing the lung,and lung-kidney yin deficiency.Correspondingly,Chaimai Jinluo Runfei Decoction(柴麦金络润肺汤)is used to nourish yin and moisten the lung;Qigui Peitu Huayin Decoction(芪桂培土化饮汤)is used to fortify the spleen and tonify the lung,resolve dampness and dispel phlegm;Chaidan Shuyu Runjin Decoction(柴丹疏郁润金汤)is used to drain liver and clear the lung;and Dimai Jinshui Xiangsheng Decoction(地脉金水相生汤)is used to nourish the kidney and moisten the lung.关键词
免疫检查点抑制剂/肺炎/咳嗽/名医经验/王晞星Key words
immune checkpoint inhibitor/pneumonitis/cough/experience of famous doctors/WANG Xixing引用本文复制引用
祁雪,王晞星,杨晞,王馨悦,张东信,毛雨兴,韩鸳鹍,翟文博,吕柏洋,李宜放..王晞星从"五脏致咳"辨治免疫检查点抑制剂相关性肺炎经验[J].中医杂志,2026,67(5):477-481,5.基金项目
国家中医药管理局国医大师传承工作室建设项目(国中医药办人教函[2022]245号) （国中医药办人教函[2022]245号）
山西省中医药管理局科研课题计划(2023ZYYC007) （2023ZYYC007）
