中医杂志2026，Vol.67Issue(5)：492-497,6.DOI:10.13288/j.11-2166/r.2026.05.006
从"痰毒流注"理论探析进展期胃癌的中医病机演变与转移机制
Analysis of Traditional Chinese Medicine Pathogenesis Evolution and Metastasis Mechanisms in Advanced Gastric Cancer from the Perspective of the"Phlegm-Toxin Flowing Infusion"Theory
摘要
Abstract
This article systematically explores the traditional Chinese medicine(TCM)pathogenesis evolution and metastatic mechanisms of advanced gastric cancer from the perspective of"phlegm-toxin flowing infusion".Based on this theory,it is proposed that advanced gastric cancer presents a pathogenesis evolution characterized by healthy qi depletion,phlegm-toxin flowing infusion,and collateral damage with blood stasis.Healthy qi depletion is the root of the disease,in which spleen and kidney insufficiency leads to weakened healthy qi and inability to resist patho-genic factors.Phlegm-toxin flowing infusion is the core pathogenesis,where phlegm-dampness and cancer toxin inter-twine and migrate to other organs along with qi movement.Collateral damage with blood stasis constitutes the final pathological stage of metastasis,where phlegm-toxin obstruction damages the collaterals,and congealed qi and blood form accumulations.On this basis,the meridian pathways and metastasis mechanisms of advanced gastric can-cer spreading to multiple sites such as the liver,peritoneum,lungs,bones,brain,ovary,and lymph nodes are further analyzed,providing references for clinical management and research of this disease.关键词
胃癌/肿瘤转移/痰毒流注Key words
gastric cancer/tumor metastasis/phlegm-toxin flowing infusion引用本文复制引用
闫星羽,王文萍..从"痰毒流注"理论探析进展期胃癌的中医病机演变与转移机制[J].中医杂志,2026,67(5):492-497,6.基金项目
辽宁省中医药交叉创新团队项目(LNZYYCXTD-JCCX-002) （LNZYYCXTD-JCCX-002）
2022辽宁省中医大师(辽宁省名中医)传承工作室建设项目(辽中医药综合字[2021]32号) （辽宁省名中医）
