安徽农业科学2026，Vol.54Issue(5)：1-5,5.DOI:10.3969/j.issn.0517-6611.2026.05.001
昆虫谷胱甘肽-S-转移酶的抗药性机制及其在害虫防治中的应用研究进展
Research Progress on Drug Resistance Mechanism of Insect Glutathione S-transferase and Its Applications in Pest Management
摘要
Abstract
This article presents a comprehensive review of the polymorphism,structural characteristics,enzymatic reaction mechanism,and regulatory roles of insect glutathione S-transferases(GSTs)in the physiological and biochemical activities of insects.The paper provides a de-tailed account of the involvement of insect GSTs in mechanisms related to pest resistance to pesticides and explores their potential as targets for pesticide action.Furthermore,it discusses the prospects for utilizing GSTs in pest management strategies including the development of GST in-hibitors,application of gene editing technology,formulation of integrated pest management strategies,and development of eco-friendly control methods.Finally,the paper proposes future research directions aimed at providing scientific evidence and technical support for innovative pest control strategies.关键词
昆虫谷胱甘肽-S-转移酶/害虫防治/抗药性Key words
Insect glutathione S-transferases/Pest control/Drug resistance分类
生物科学引用本文复制引用
孙美娣,宋志芹,高雯芳,李敏,潘丽娜..昆虫谷胱甘肽-S-转移酶的抗药性机制及其在害虫防治中的应用研究进展[J].安徽农业科学,2026,54(5):1-5,5.基金项目
国家自然科学基金项目(31702058) （31702058）
天津市应用基础计划面上项目(18JCYBJC96300) （18JCYBJC96300）
天津市教委科研计划项目(2019KJ089,2022KJ013). （2019KJ089,2022KJ013）
