巴楚医学2026,Vol.9Issue(1):1-9,9.DOI:10.3969/j.issn.2096-6113.2026.01.001
代谢失衡:从分子机制到多系统疾病干预的研究新范式
Metabolic Imbalance:A New Research Paradigm from Molecular Mechanisms to Multi-System Disease Intervention
饶克勤1
作者信息
- 1. 清华大学医院管理研究院,广东 深圳 518055
- 折叠
摘要
Abstract
Metabolic imbalance,as a core issue of modern medicine,drives the occurrence of multi-system diseases by disrupting the homeostasis of material and energy metabolism.This article systematically integrates the latest research,revealing that metabolic imbalance forms a bidirectional regulatory network with diseases such as cerebral infarction,chronic kidney disease,and diabetes through pathways like insulin resistance,inflammatory cascades,and oxidative stress.Current research focuses on the analysis of molecular mechanisms and the development of individualized intervention strategies,but breakthroughs are still needed in areas such as individual heterogeneity and the interaction between microbiota and metabolism.This review aims to construct a comprehensive cognitive framework of"metabolic imbalance-disease occurrence-precise management",providing a theoretical basis for clinical translation.关键词
代谢失衡/多系统疾病/病理机制/精准干预Key words
metabolic imbalance/multi-system diseases/pathological mechanism/precision intervention分类
医药卫生引用本文复制引用
饶克勤..代谢失衡:从分子机制到多系统疾病干预的研究新范式[J].巴楚医学,2026,9(1):1-9,9.