巴楚医学2026，Vol.9Issue(1)：76-82,7.DOI:10.3969/j.issn.2096-6113.2026.01.010
中老年人群握力和甘油三酯-葡萄糖指数与全因死亡率的联合关联性分析
Analysis of the Joint Association of Grip Strength and Triglyceride Glucose Index with All Cause Mortality among Middle Aged and Elderly People
摘要
Abstract
Objective:To explore the joint association between grip strength and triglyceride glucose(TyG)index with all cause mortality among middle aged and elderly people aged 45 and above in China,and to provide a scientific basis for health management and preventive intervention strategies for this population.Methods:A total of 8 392 middle aged and elderly people aged 45 and above from the China Health and Retirement Longitudinal Study(CHARLS)database from 2011 to 2020 were selected.They were divided into a survival group(n=7 348)and a death group(n=1 028)according to whether they died during the follow up period.Three model corrections were carried out according to age,gender,educational level,marital status,etc.Cox regression was used to analyze the joint association between grip strength,TyG index and all cause mortality risk.Results:Decreased grip strength and increased TyG index could significantly increase the risk of all cause mortality.In Model 3,compared with those with normal grip strength,the hazard ratio(HR)of those with decreased grip strength was 1.84(95％CI:1.61,2.10).Compared with those with low TyG,the HR of those with high TyG was 1.24(95％CI:1.07,1.44).Among those with low TyG,compared with those with normal grip strength,the HR of those with decreased grip strength was 1.76(95％CI:1.45,2.13).Among those with high TyG,compared with those with normal grip strength,the HR of those with decreased grip strength was 1.87(95％CI:1.55,2.26).Compared with those with normal grip strength-low TyG,the HRs of those with normal grip strength-high TyG,decreased grip strength-low TyG and decreased grip strength-high TyG were 1.23(95％CI:1.02,1.48),1.85(95％CI:1.54,2.22)and 2.24(95％CI:1.83,2.73),respectively.Conclusion:Decreased grip strength and increased TyG index significantly increase the mortality risk of middle aged and elderly people.关键词
握力/甘油三酯-葡萄糖指数/全因死亡率/联合关联Key words
grip strength/triglyceride-glucose(TyG)index/all-cause mortality/joint association分类
医药卫生引用本文复制引用
刘静,朱武飞,周高生..中老年人群握力和甘油三酯-葡萄糖指数与全因死亡率的联合关联性分析[J].巴楚医学,2026,9(1):76-82,7.基金项目
中央引导地方科技发展专项(2022BGE237) （2022BGE237）
湖北省自然科学基金项目(2023AFC003 （）
2024AFB361) （）
