大学化学2026，Vol.41Issue(3)：297-306,10.DOI:10.12461/PKU.DXHX202504078
固相微萃取与质谱联用技术在环境检测中的应用
Application of Solid-Phase Microextraction and Mass Spectrometry in Environmental Detection
摘要
Abstract
Solid-phase microextraction(SPME)represents an integrated sample pretreatment technology combining extraction,concentration,desorption,and sampling processes in a single step.Characterized by operational simplicity,cost-effectiveness,high efficiency,and minimal solvent requirements,this technique has emerged as a critical analytical tool in environmental sciences since its initial development in the 1990s by Belardi and Pawliszyn at the University of Waterloo,Canada.The integration of SPME with mass spectrometry(MS)enables effective detection and quantitative analysis of environmental pollutants,establishing a robust methodology for environmental monitoring.This review systematically examines the fundamental principles of SPME technology,including its extraction mechanisms and advanced coating materials.It further analyzes three principal hyphenated techniques(SPME-GC-MS,SPME-LC/HPLC-MS,and SPME-AMS)through their operational characteristics and environmental application case studies.The paper concludes with a critical perspective on future research directions,focusing on technical optimization and expanded implementation potential in environmental analytical chemistry.关键词
样品前处理/固相微萃取/涂层/质谱Key words
Sample pretreatment/Solid phase microextraction/Coating/Mass spectrometry分类
社会科学引用本文复制引用
侯思维,牛雅新,张广录,杨燕美,王栩,陈蓁蓁..固相微萃取与质谱联用技术在环境检测中的应用[J].大学化学,2026,41(3):297-306,10.基金项目
山东省自然科学基金项目(ZR2024MB152),山东省本科教学改革研究重点项目(Z2023098) （ZR2024MB152）
