华中农业大学学报2026，Vol.45Issue(2)：37-44,8.DOI:10.13300/j.cnki.hnlkxb.2026.02.005
前臀鮡上颌和胸鳍特化皮肤组织结构特征和基因表达调控
Structural characteristics and gene expression regulation of skin specialization in Pareuchiloglanis anteanalis
摘要
Abstract
Pareuchiloglanis anteanalis is an endangered endemic species native to the upper Yangtze River.To adapt to fast-flowing highland river environment,the skin structures in its upper jaw and fin-ray regions have undergone specialization,providing strong adhesive capabilities.To elucidate the regulatory ba-sis of this specialization,we examined the histological features of the specialized skin,performed compara-tive transcriptomic analyses between specialized skin(from the upper jaw and pectoral fin)and non-special-ized skin(from the fin-ray region),screened and identified genes associated with skin specialization.The re-sults showed that the specialized epidermis of the upper jaw and pectoral fin develops dense ridges,grooves and sensory bud structures,which enhance adhesion.Tissue-origin mapping showed that these specialized tissues formed adjacent clusters with highly similar gene expression profiles and strong homology.Compared to the non-specialized skin from the fin-ray region,the upper jaw and pectoral fin shared 251 differentially expressed genes(DEGs),including 146 upregulated and 105 downregulated genes.KEGG enrichment anal-ysis indicated that the significantly enriched pathways were primarily purine metabolism(ko00230),TGF-β signaling pathway(ko04350),and calcium signaling pathway(ko04020).qRT-PCR validation con-firmed that adcy5 was significantly upregulated in the specialized skin(P<0.05).In summary,P.anteana-lis develops dense epidermal ridge-groove structures and sensory buds in the upper jaw and pectoral fin to enhance adhesion,adapting to the fast-flowing highland river environment.This skin specialization process is primarily driven by key pathways such as cell projection assembly and collagen metabolism,and the sig-nificant upregulation of adcy5 suggests its potential regulatory role in skin specialization.关键词
前臀鮡/皮肤特化/组织结构/基因表达Key words
Pareuchiloglanis anteanalis/skin specialization/histological features/gene expression分类
生物科学引用本文复制引用
王聪,李顺尧,熊雪梅,杨瑞斌,高泽霞,熊皓,赵恒,万世明..前臀鮡上颌和胸鳍特化皮肤组织结构特征和基因表达调控[J].华中农业大学学报,2026,45(2):37-44,8.基金项目
国家自然科学基金面上项目(32473145) （32473145）
华电集团金沙江上游远期放流鱼种人工繁育技术研究项目(T-2022-04) （T-2022-04）
