实用临床医药杂志2026，Vol.30Issue(4)：111-114,4.DOI:10.7619/jcmp.20256181
孕晚期超声生物测量联合血流动力学指标预测分娩足月小于胎龄儿的效能分析
Efficacy of ultrasound biometric measurements combined with hemodynamic indices in late pregnancy for predicting the delivery of full-term small for gestational age infants
摘要
Abstract
Objective To investigate the efficacy of fetal biometric measurements combined with Doppler hemodynamic indices in late pregnancy for predicting the delivery of full-term small for gesta-tional age(SGA)infants.Methods A retrospective analysis was conducted in 80 pregnant women who delivered full-term SGA infants in the Maternal and Child Healthcare Hospital of Tongzhou District in Beijing from June 2023 to December 2024(case group),and another 80 pregnant women who de-livered full-term appropriate for gestational age(AGA)infants during the same period(within 2 weeks)were selected as control group.Fetal biometric measurements[biparietal diameter(BPD),head circumference(HC),abdominal circumference(AC),and femoral length(FL)]and Doppler he-modynamic indices[pulsatility index(PI)and resistance index(RI)of the umbilical artery(UA)and fetal middle cerebral artery(MCA)]in late pregnancy(28 to 32 weeks of gestation)were compared be-tween the two groups.The predictive efficacy of these indices for full-term SGA was analyzed using re-ceiver operating characteristic(ROC)curve.Results There were no significant differences in maternal age,gravidity,parity,mode of delivery,gestational age at delivery,and pregnancy complications between the case and control groups(P＞0.05).However,a significant difference was observed in neonatal birth weight between the two groups(P＜0.01).In the case group,fetal biometric meas-urements(BPD,HC,AC,and FL)in late pregnancy were significantly lower than those in the control group(P＜0.01).The PI and RI of the UA in late pregnancy in the case group were signifi-cantly higher than those in the control group,while the PI and RI of the MCA were significantly low-er(P＜0.01).The area under the curve(AUC)for the combined ultrasound indices in predicting the delivery of full-term SGA infants in late pregnancy was 0.909,which was significantly higher than AUC values for individual measurement of BPD(0.749),HC(0.755),AC(0.799),FL(0.783),UA-PI(0.828),UA-RI(0.807),MCA-PI(0.810),or MCA-RI(0.799)(P＜0.05).Conclusion Fetal biometric measurements combined with Doppler hemodynamic indices in late pregnancy can reflect fetal intrauterine growth status and provide high accuracy in predicting the occurrence of full-term SGA.关键词
小于胎龄儿/适于胎龄儿/胎儿生长受限/双顶径/头围/脐动脉/大脑中动脉/搏动指数/阻力指数Key words
small for gestational age infant/appropriate for gestational age infant/fetal growth restriction/biparietal diameters/head circumference/umbilical artery/middle cerebral artery/pul-satility index/resistance index分类
医药卫生引用本文复制引用
陈晓春,陈炫嘉,朱毓,杨立..孕晚期超声生物测量联合血流动力学指标预测分娩足月小于胎龄儿的效能分析[J].实用临床医药杂志,2026,30(4):111-114,4.基金项目
北京市通州区科技计划项目(KJ2023CX071) （KJ2023CX071）
