临床误诊误治2026，Vol.39Issue(7)：40-46,7.DOI:10.3969/j.issn.1002-3429.2026.07.007
LSaO2、BCVA、RNFL及CRA流速对视网膜静脉阻塞患者合并阻塞性睡眠呼吸暂停低通气综合征的预测价值
Predictive value of LSaO2,BCVA,RNFL and CRA flow velocity in patients with retinal vein occlusion complicated with obstructive sleep apnea hypopnea syndrome
摘要
Abstract
Objective To compare the differences of lowest oxygen saturation(LSaO2),best corrected visual acuity(BCVA),retinal nerve fiber layer thickness(RNFL),peak systolic velocity(PSV)and end diastolic velocity(EDV)of central retinal artery(CRA)between retinal vein occlusion(RVO)patients with and without obstructive sleep apnea hypopnea syndrome(OSAHS),and to analyze their predictive value for combined OSAHS.Methods A total of 180 patients with RVO treated from June 2020 to June 2023 were selected and divided into OSAHS group(n=83)and non-OSAHS group(n=97)according to the presence or absence of OSAHS.The baseline data,LSaO2,BCVA,RNFL,CRA-PSV,CRA-EDV and apnea hypopnea index(AHI)were compared between the two groups.The relationship of LSaO2,BCVA,RNFL,CRA-PSV,CRA-EDV with AHI in patients with RVO complicated with OSAHS was analyzed.The predictive value of LSaO2,BCVA,RNFL,CRA-PSV and CRA-EDV for the risk of RVO combined with OSAHS was evaluated.Results The body mass index,proportion of hypertension,age,proportion of hyperlipidemia and AHI in the OSAHS group were higher than those in the non-OSAHS group,while LSaO2,BCVA,RNFL,CRA-PSV and CRA-EDV were lower than those in the non-OSAHS group(P<0.05).Pearson correlation analysis showed that LSaO2,BCVA,RNFL,CRA-PSV,and CRA-EDV were negatively correlated with AHI(P<0.05).After adjusting for other factors,multivariate logistic regression analysis showed that LSaO2,BCVA,RNFL,CRA-PSV and CRA-EDV were all influencing factors of RVO combined with OSAHS(P<0.05).The area under the curve of LSaO2,BCVA,RNFL,CRA-PSV and CRA-EDV in predicting the risk of RVO combined with OSAHS was 0.917(95%CI:0.866,0.953),which was greater than that of each index alone(P<0.05).Conclusion LSaO2,BCVA,RNFL,CRA-PSV and CRA-EDV are closely related to AHI in patients with RVO complicated with OSAHS.The combination of each index is helpful to improve the predictive value for RVO complicated with OSAHS.关键词
视网膜静脉阻塞/阻塞性睡眠呼吸暂停低通气综合征/血氧饱和度/视力/视神经纤维层厚度/视网膜动脉/预测Key words
retinal vein occlusion/obstructive sleep apnea hypopnea syndrome/blood oxygen saturation/vision/retinal nerve fiber layer thickness/retinal artery/prediction引用本文复制引用
树玲博,崔明霞,李楠,段颖,张阳,任国英,冯会超..LSaO2、BCVA、RNFL及CRA流速对视网膜静脉阻塞患者合并阻塞性睡眠呼吸暂停低通气综合征的预测价值[J].临床误诊误治,2026,39(7):40-46,7.基金项目
衡水市重点研发计划项目(2023014067Z) （2023014067Z）
河北省2022年度医学科学研究课题计划(20220448) （20220448）
