临床肝胆病杂志2026,Vol.42Issue(2):272-277,6.DOI:10.12449/JCH260204
丁型肝炎患者的临床管理
Clinical management of patients with hepatitis D
摘要
Abstract
Hepatitis D virus(HDV),as a defective virus,relies on the envelope protein of hepatitis B virus(HBV)to complete replication and transmission.Chronic hepatitis B(CHB)patients comorbid with HDV infection may experience significant acceleration of liver disease progression and a significantly higher risk of serious complications such as liver cirrhosis and hepatocellular carcinoma(HCC)compared with the patients with CHB alone,which poses a serious threat to the life and health of patients.At present,the coverage rate of HDV screening needs to be improved,and some patients with HBV/HDV co-infection have not been found in time.Therefore,strengthening the understanding of HDV among clinicians,expanding the scope of HDV screening,identifying patients with infection in a timely manner,and performing standardized antiviral therapy and long-term follow-up management are of great significance for improving the prognosis of patients,reducing disease burden,improving the quality of life of patients,and achieving the global goal of"eliminating viral hepatitis as a public health threat by 2030".关键词
丁型肝炎/普查/诊断/治疗学/临床管理Key words
Hepatitis D/Mass Screening/Diagnosis/Therapeutics/Clinical Governance引用本文复制引用
吴旭,窦婧,郭峰,胡西百合提,王晓忠..丁型肝炎患者的临床管理[J].临床肝胆病杂志,2026,42(2):272-277,6.基金项目
新疆维吾尔自治区"天山英才"医药卫生高层次人才培养计划(TSYC202401B161) Xinjiang Uygur Autonomous Region"Tianshan Elite"High-level Medical and Health Personnel Training Program(TSYC202401B161) (TSYC202401B161)