内科理论与实践2026，Vol.21Issue(1)：68-73,6.DOI:10.16138/j.1673-6087.2026.01.10
获得性免疫缺陷综合征相关卡波西肉瘤多器官受累特征与诊疗策略
Features of multi-organ involvement and management strategies in AIDS-related Kaposi sarcoma
摘要
Abstract
Kaposi sarcoma(KS)is a multicentric tumor closely associated with immunosuppression and KS-associated herpesvirus(KSHV)infection.The synergistic interaction between KSHV infection and human immunodeficiency virus(HIV)infection promotes the occurrence and progression of acquired immunodeficiency syndrome(AIDS)-associated KS(AIDS-KS).AIDS-KS is one of the most common malignancies in AIDS patients and thus requires high clinical attention.This article systematically reviews the multicentric pathogenesis of AIDS-KS,the specific clinical manifestations of involvement in different organs and stratified diagnostic and therapeutic strategies,with particular emphasis on the importance of combining antiretroviral therapy(ART)and targeted therapy in disease management.The implementation of individualized and multidisciplinary comprehensive management strategies can better control disease progression and improve patients'quality of life as well as prognosis.关键词
获得性免疫缺陷综合征/卡波西肉瘤/发病机制/器官受累/抗逆转录病毒治疗/诊疗策略Key words
acquired immunodeficiency syndrome/Kaposi sarcoma/pathogenesis/organ involvement/antiretroviral therapy/diagnostic and therapeutic strategies分类
医药卫生引用本文复制引用
张亚萍,王力,何沅鸿,尹科,杨彤彤..获得性免疫缺陷综合征相关卡波西肉瘤多器官受累特征与诊疗策略[J].内科理论与实践,2026,21(1):68-73,6.基金项目
四川省临床重点专科建设项目(2023AGRKP001) （2023AGRKP001）
