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衰老异质性的研究进展

王廷旭 王旭 周廉尧 尹硕 代敬宇 叶静

内科理论与实践2026,Vol.21Issue(1):74-79,6.
内科理论与实践2026,Vol.21Issue(1):74-79,6.DOI:10.16138/j.1673-6087.2026.01.11

衰老异质性的研究进展

Research progress on heterogeneity of aging

王廷旭 1王旭 1周廉尧 1尹硕 2代敬宇 2叶静3

作者信息

  • 1. 上海交通大学医学院,上海 200025
  • 2. 上海交通大学生物医学工程学院,上海 200241
  • 3. 上海交通大学医学院附属瑞金医院老年科,上海 200025
  • 折叠

摘要

Abstract

With the development of Chinese society,the proportion of the population aged 65 and above is increasing,and China is gradually entering an aging society.How to achieve healthy aging and how to delay aging have become important social issues.Due to the heterogeneity of aging,different individuals have different rates of aging.Aging is jointly regulated by internal and external factors.The internal factors include the twelve classic characteristics of aging,and there are multiple aging"clocks"that can indicate the level of cellular senescence.Therefore,the internal factors are clearly studied at present.The external factors include contributing factors and harmful factors.At present,the research on external factors is less and more concentrated in specific risk areas,and the research on the real situation is relatively limited.External factors interact with internal factors to influence aging.The use of multivariate cross analysis calculation to establish a comprehensive model of the interaction between internal and external factors of aging in a universal environment can provide theoretical support and technical means for the prevention and early warning of aging and related diseases.

关键词

衰老/分子标志物/环境

Key words

aging/molecular marker/environment

分类

医药卫生

引用本文复制引用

王廷旭,王旭,周廉尧,尹硕,代敬宇,叶静..衰老异质性的研究进展[J].内科理论与实践,2026,21(1):74-79,6.

基金项目

上海交通大学医学院大学生创新训练计划(1723Y091) (1723Y091)

内科理论与实践

1673-6087

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