山东中医杂志2026，Vol.45Issue(3)：268-272,276,6.DOI:10.16295/j.cnki.0257-358x.2026.03.008
基于"因加而发"探讨高尿酸血症—痛风"浊毒转化"防治
Discussion on Prevention and Treatment of Turbid Toxin Transformation in Hyperuricemia-Gout Based on"Onset Due to the Combination of Pathogenic Factors"
摘要
Abstract
The concept of"onset due to the combination of pathogenic factors"originated from The Yellow Emperor's Canon of Internal Medicine,which explains that the occurrence of diseases is closely related to the stimulation of new pathogenic factors by existing ones.Over time,successive medical practitioners have enriched and expanded its content through clinical practice,and it has been used ever since.The occurrence of hyperuricemia and gout is closely related to the gradual depletion of healthy qi and the presence of dampness,heat,and stasis.The"dampness"in hyperuricemia refers to the latent pathogenic factors within the body.After being provoked by new pathogens,the body's healthy qi is unable to expel the pathogenic factors,resulting in the generation of heat and stasis.This process involves the transfor-mation from turbidity to toxicity.When the new and old pathogens combine,it leads to the onset of gout.This is in line with the"onset due to the combination of pathogenic factors"theory of disease occurrence.Therefore,in clinical diagnosis and treatment,one should seize the opportunity to intervene promptly in the early stage of the disease to prevent transmission.Based on the principle of clearing heat,eliminating dampness,and transforming turbidity,the four methods of penetrating,clearing,eliminating,and tonifying should be flexibly applied to address both the symptoms and the root causes.This ensures prevention of disease before it occurs,control of disease progression after it occurs,and prevention of recurrence after recovery.It involves attacking the pathogen before it becomes too strong,supporting the body before it becomes too weak,and focusing on care and maintenance after recovery to delay the process of"turbidity-toxicity transformation".关键词
高尿酸血症/痛风/因加而发/治未病/浊毒转化Key words
hyperuricemia/gout/onset due to the combination of pathogenic factors/preventive treatment of disease/turbidity-toxicity transformation分类
医药卫生引用本文复制引用
牛源源,杜明瑞..基于"因加而发"探讨高尿酸血症—痛风"浊毒转化"防治[J].山东中医杂志,2026,45(3):268-272,276,6.基金项目
河南省中医药传承与创新人才工程(仲景工程)中医药学科拔尖人才(编号:CZ0237-15) （仲景工程）
河南省中医药科学研究专项课题(编号:2018ZY2060) （编号:2018ZY2060）
河南省卫生健康委员会基地专项课题(编号:2021JDZY083) （编号:2021JDZY083）
