世界针灸杂志（英文版）2026，Vol.36Issue(1)：1-9,9.DOI:10.1016/j.wjam.2025.12.003
针灸在化疗诱发性恶心与呕吐防治中的治疗作用
Therapeutic roles of acupuncture in the treatment of chemotherapy induced nausea and vomiting
摘要
Abstract
Chemotherapy-induced nausea and vomiting(CINV)remains one of the most disruptive complications during cancer treatment,often persisting despite standard antiemetic regimens.As clinical practice seeks supplementary strategies to enhance symptom control,acupuncture and moxibustion have emerged as promising adjunctive therapies.Existing trials and meta-analyses indicate their therapeutic potential,yet the neurobiological basis for these effects has not been fully elucidated.This study synthesizes current evidence to outline how acupuncture and moxibustion intervene in the peripheral and central path-ways involved in CINV.Particular attention is given to their regulatory influence on vagal afferent sig-naling,gastrointestinal sensory pathways,and key neurotransmitter systems,such as 5-HT,SP,DA,and GABA,alongside modulation of brainstem nuclei and higher-order neural circuits implicated in emetic responses.The analysis also identifies procedural and methodological constraints in present clinical stud-ies and highlights unresolved mechanistic questions.By integrating findings from neurophysiology and oncology-related symptom research,this review offers a foundation for more precise mechanistic inves-tigations and for optimizing acupuncture-based interventions in CINV management.关键词
Chemotherapy-induced nausea and vomiting/Acupuncture/Anti-emetic mechanism/Traditional Chinese medicineKey words
Chemotherapy-induced nausea and vomiting/Acupuncture/Anti-emetic mechanism/Traditional Chinese medicine引用本文复制引用
柏灿,魏奕彤,张彩娟..针灸在化疗诱发性恶心与呕吐防治中的治疗作用[J].世界针灸杂志（英文版）,2026,36(1):1-9,9.基金项目
Supported by Natural Science Research Project of the Anhui Educational Com-mittee:2023AH050850,2022AH050514. （）
