世界针灸杂志(英文版)2026,Vol.36Issue(1):18-28,11.DOI:10.1016/j.wjam.2025.12.001
灸法干预化疗所致骨髓抑制:一项系统评价与Meta分析
Moxibustion for chemotherapy-induced myelosuppression:A systematic review and meta-analysis
摘要
Abstract
Objective:To evaluate the effectiveness and safety of moxibustion for chemotherapy-induced myelosup-pression. Methods:The randomized controlled trials of moxibustion for chemotherapy-induced myelosuppression were searched in PubMed,Cochrane Library,Web of Science,Embase,China Journal Full-text Database,SinoMed,Wanfang Data Knowledge Service Platform,and VIP Chinese Journal Service Platform,from the inception of each database to July 30,2024.RevMan5.3 and Stata18.0 were used for meta-analysis,and the quality of included literature was evaluated by Cochrane Risk of Bias(RoB)assessment tool. Results:A total of 19 articles were included.Moxibustion can increase white blood cell count(MD=1.06,95%CI:0.45-1.68,P=0.0007),platelet count(MD=32.02,95%CI:16.33-47.72,P<0.00001),hemoglobin content(MD=5.57,95%CI:1.61-9.53,P=0.006)and neutrophil count(MD=1.20,95%CI:0.94-1.45,P<0.00001).Moxibustion could alleviate chemotherapy-induced myelosuppression(RR=0.70,95%CI:0.56-0.86,P=0.0007),reduced the incidences of leukopenia(RR=0.39,95%CI:0.26-0.59,P<0.000001)and thrombocytopenia(RR=0.33,95%CI:0.21-0.53,P<0.000001),and can improve the score of quality of life(MD=0.55,95%CI:0.32-0.79,P<0.00001). Conclusion:Moxibustion can increase the white blood cell count,platelet count,hemoglobin content and neutrophil count of patients after chemotherapy,alleviate myelosuppression,and the incidences of leukopenia and thrombocytopenia induced by chemotherapy,and improve the quality of life.Moxibus-tion is effective and safe for chemotherapy-induced myelosuppression.However,due to the relatively low quality of included studies,there are certain limitations.More high-quality studies are needed in the future to provide more reliable evidence-based basis for clinical practice.关键词
Myelosuppression/Post-chemotherapy/Moxibustion/Tumor/Systematic review/Meta analysisKey words
Myelosuppression/Post-chemotherapy/Moxibustion/Tumor/Systematic review/Meta analysis引用本文复制引用
薛丹,蓝荣林,胡华涛,张云彬,黄仙保..灸法干预化疗所致骨髓抑制:一项系统评价与Meta分析[J].世界针灸杂志(英文版),2026,36(1):18-28,11.基金项目
Supported by the National Natural Science Foundation of China:82260969 ()
the Science and Technology Plan Project(Key Project)of Jiangxi Provincial Ad-ministration of Traditional Chinese Medicine:2022Z022 (Key Project)
the Standardization Project of Jiangxi Provincial Standardization Technical Committee for Traditional Chinese Medicine:2024A017 ()
and the Key Discipline Construction Funding Project of Jiangxi University of Traditional Chinese Medicine:2023jzzdxk036. ()