天津中医药2026，Vol.43Issue(4)：419-424,6.DOI:10.11656/j.issn.1672-1519.2026.04.03
国医大师王晞星基于"脏腑别通"理论从"药毒"论治化疗相关性腹泻
Chinese medicine master WANG Xixing treating chemotherapy-related diarrhoea from the perspective of"drug toxicity"based on the theory of"zang-fu extea-ordinary connection"
摘要
Abstract
Chemotherapy-induced diarrhea(CID)is a common adverse reaction to chemotherapy.Mild cases impair patients'quality of life and disrupt treatment schedules,while severe cases may be life-threatening.Current Western medicine primarily relies on symptomatic management with limited efficacy.Expanding the traditional concept of zang-fu relationships in traditional Chinese medicine(TCM),this study innovatively analyzes CID through the lens of the"zang-fu extea-ordinary connection"theory(viscera interconnection beyond conventional pairings).By correlating the cold/heat nature of chemotherapeutic agents,the pathological mechanisms are explored via four pathways:spleen-small intestine,kidney-triple energizer,liver-large intestine,and heart-gallbladder.Specifically,cold-natured chemotherapeutics initially impair spleen yang,leading to dysfunction of the small intestine in regulating fluids;in later stages,they damage kidney yang,obstructing triple energizer's water metabolism.Heat-natured agents trigger liver fire hyperactivity(causing large intestine dysmotility)and heart fire excess(resulting in gallbladder heat descending to the large intestine).Clinically,targeted therapies are proposed:strengthening spleen yang to regulate small intestine function,tonifying kidney yang to promote triple energizer's qi transformation,clearing liver fire to restore large intestine motility,and purging heart fire to normalize gallbladder heat.Modified formulas such as Shengyang Zhixie Formula,Bushen Lishui Decoction,Gegen Qinlian Decoction,and Chaihu Qingdan Decoction are applied with marked efficacy.关键词
化疗相关性腹泻/脏腑别通/药毒/名医经验Key words
chemotherapy-associated diarrhea/zang-fu extea-ordinary connection/drug poisons/famous doctor experience分类
医药卫生引用本文复制引用
刘懿婵,王海燕,石智尧,高宇,王晞星..国医大师王晞星基于"脏腑别通"理论从"药毒"论治化疗相关性腹泻[J].天津中医药,2026,43(4):419-424,6.基金项目
第四届国医大师传承工作室(国中医药办人教函[2022]245号1123-04) （国中医药办人教函[2022]245号1123-04）
国家中医药传承创新中心的建设(202203) （202203）
山西省卫生健康委员会山西省医学科技创新团队项目(2020TD04) （2020TD04）
国家中医临床研究基地(山西省中医院)专项任务书(JDZXLC-01) （山西省中医院）
山西省中医药研究院院内项目(202306). （202306）
