现代医药卫生2026，Vol.42Issue(3)：535-539,5.DOI:10.3969/j.issn.1009-5519.2026.03.012
主动脉内球囊反搏术对预防瓣膜置换术后低心排综合征的临床效果研究
Clinical effect of intra-aortic balloon counterpulsation in preventing low cardiac output syndrome after valve replacement surgery
摘要
Abstract
Objective To explore the clinical efficacy of intra-aortic balloon counterpulsation(IABP)in preventing secondary low cardiac output syndrome(LCOS)after valve replacement surgery.Methods A total of 115 patients with heart valve disease admitted to our hospital from February 2022 to June 2024 were en-rolled in a prospective randomized controlled trial.According to the patients'conditions and surgical willing-ness,they were divided into the conventional group of 57 cases and the IABP group of 58 cases.The conven-tional group underwent routine heart valve replacement surgery,while the IABP group underwent IABP-assis-ted heart valve replacement surgery.All patients were followed up for six months after treatment.Hemody-namic parameters,myocardial injury markers,clinical indicators,and cardiac function recovery were compared between the two groups.Results After treatment,the mean arterial pressure,heart rate,cardiac output,and cardiac index in the IABP group were significantly higher than those in the conventional group,while cardiac troponin T,creatine kinase isoenzyme,lactate dehydrogenase,and ischemia-modified albumin were significant-ly lower than those in the conventional group,with statistically significant differences(P<0.05).The intrao-perative dosage of vasoactive substances,postoperative assisted ventilation time,ICU stay duration,hospital stay duration,and incidence of LCOS in the IABP group were better than those in the conventional group,with statistically significant differences(P<0.05).At the end of follow-up,the left ventricular ejection fraction and early diastolic/late diastolic flow velocity ratio in the IABP group were higher than those in the conven-tional group,while the left ventricular end-diastolic volume and left ventricular end-systolic volume were low-er than those in the conventional group,with statistically significant differences(P<0.05).Conclusion IABP-as-sisted valve replacement surgery can improve hemodynamics and reduce myocardial damage in patients with heart valve disease.It plays a positive role in reducing the intraoperative dosage of vasoactive substances,ac-celerating postoperative recovery process,decreasing the risk of LCOS,and promoting cardiac function recov-ery in patients.关键词
瓣膜置换术/主动脉内球囊反搏术/血流动力学/心肌损伤/心功能Key words
Valve replacement surgery/Intra-aortic balloon counterpulsation/Hemodynamics/Myocardial injury/Cardiac function分类
医药卫生引用本文复制引用
冯永飞,张丁乾,潘丽红..主动脉内球囊反搏术对预防瓣膜置换术后低心排综合征的临床效果研究[J].现代医药卫生,2026,42(3):535-539,5.基金项目
河南省医学科技攻关计划项目(LHGJ20200552、SBGJ202302087). （LHGJ20200552、SBGJ202302087）
