摘要
Abstract
Lupus nephritis(LN)is one of the common and severe complications of systemic lupus ery-thematosus.Characterized by diverse pathological patterns and variable clinical manifestations,LN presents sig-nificant challenges for disease management.Conventional immunosuppressive agents,while representing the classic therapeutic approach for LN,are associated with substantial limitations,including variable efficacy,high risk of relapse,and notable adverse effects.In recent years,the introduction of immunotherapeutic agents,particularly biologics,has inaugurated a new era of precision treatment for LN.By virtue of their high target specificity and favorable safety profiles,these agents are reshaping the therapeutic landscape of LN.This article reviews the current status and future prospects of precision immunotherapy for LN,aiming to provide insights for its clinical management.关键词
狼疮性肾炎/系统性红斑狼疮/生物制剂/精准治疗Key words
lupus nephritis/systemic lupus erythematosus/biologic agents/precision therapy分类
医药卫生
