畜牧兽医学报2026，Vol.57Issue(3)：1187-1194,8.DOI:10.11843/j.issn.0366-6964.2026.03.002
铁死亡在畜禽卵泡发育调控中的作用及机制
Function and Mechanism of Ferroptosis in Regulating Follicular Development in Livestock and Poultry
摘要
Abstract
Ovarian folliculogenesis is fundamental to the reproductive activity of female mammals,encompassing the formation of primordial follicles,follicular recruitment,dominant follicle selection,ovulation of mature follicles,and the follicular atresia process that persists throughout development.Ferroptosis,a novel form of regulated cell death,plays a critical role in follicular development,particularly during atresia.This review systematically explores the molecular mechanisms of ferroptosis,emphasizing its impact on follicular atresia,primordial follicle activation,and oocyte maturation,as well as the regulatory effects of antioxidants on ferroptosis.The aim is to provide a theoretical reference for further research in this domain.关键词
铁死亡/卵泡发育/颗粒细胞/调控机制Key words
ferroptosis/follicular development/granulosa cells/regulation mechanism分类
农业科技引用本文复制引用
罗润箫,李利,张红平,占思远..铁死亡在畜禽卵泡发育调控中的作用及机制[J].畜牧兽医学报,2026,57(3):1187-1194,8.基金项目
国家重点研发计划项目(2021YFD1600703) （2021YFD1600703）
